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http://purl.uniprot.org/citations/3096579http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3096579http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3096579http://www.w3.org/2000/01/rdf-schema#comment"Krüppel (Kr), a segmentation gene of Drosophila, encodes a protein sharing structural features of the DNA-binding "finger motif" of TFIIIA, a Xenopus transcription factor. Low-stringency hybridization of the Kr finger coding sequence revealed multiple copies of homologous DNA sequences in the genomes of Drosophila and other eukaryotes. Molecular analysis of one Kr-homologous DNA clone identified a developmentally regulated gene. Its product, a finger protein, relates to Kr by the invariant positioning of crucial amino acid residues within the finger repeats and by a stretch of seven amino acids connecting the finger loops, the "H/C link." This H/C link is conserved in several nuclear and chromosome-associated proteins of Drosophila and other eukaryotic organisms including mammals. Our results demonstrate a new subfamily of evolutionarily conserved nuclear and possibly DNA-binding proteins that again relate to a Drosophila segmentation gene as in the case of the homeo domain."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.org/dc/terms/identifier"doi:10.1016/0092-8674(86)90817-2"xsd:string
http://purl.uniprot.org/citations/3096579http://purl.org/dc/terms/identifier"doi:10.1016/0092-8674(86)90817-2"xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Jaeckle H."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Jaeckle H."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Cote S."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Cote S."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Schroeder C."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Schroeder C."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Maier D."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Maier D."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Schuh R."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Schuh R."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Preiss A."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Preiss A."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Gaul U."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Gaul U."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Kemler R."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Kemler R."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Nauber U."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Nauber U."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Seifert E."xsd:string
http://purl.uniprot.org/citations/3096579http://purl.uniprot.org/core/author"Seifert E."xsd:string