| http://purl.uniprot.org/citations/31006538 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31006538 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31006538 | http://www.w3.org/2000/01/rdf-schema#comment | "Certain proteins and organelles can be selectively degraded by autophagy. Typical substrates and receptors of selective autophagy have LC3-interacting regions (LIRs) that bind to autophagosomal LC3 and GABARAP family proteins. Here, we performed a differential interactome screen using wild-type LC3B and a LIR recognition-deficient mutant and identified TEX264 as a receptor for autophagic degradation of the endoplasmic reticulum (ER-phagy). TEX264 is an ER protein with a single transmembrane domain and a LIR motif. TEX264 interacts with LC3 and GABARAP family proteins more efficiently and is expressed more ubiquitously than previously known ER-phagy receptors. ER-phagy is profoundly blocked by deletion of TEX264 alone and almost completely by additional deletion of FAM134B and CCPG1. A long intrinsically disordered region of TEX264 is required for its ER-phagy receptor function to bridge the gap between the ER and autophagosomal membranes independently of its amino acid sequence. These results suggest that TEX264 is a major ER-phagy receptor."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molcel.2019.03.033"xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molcel.2019.03.033"xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/author | "Hatta T."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/author | "Hatta T."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/author | "Natsume T."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/author | "Natsume T."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/author | "Mizushima N."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/author | "Mizushima N."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/author | "Chino H."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/author | "Chino H."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/title | "Intrinsically disordered protein TEX264 mediates ER-phagy."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://purl.uniprot.org/core/title | "Intrinsically disordered protein TEX264 mediates ER-phagy."xsd:string |
| http://purl.uniprot.org/citations/31006538 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31006538 |
| http://purl.uniprot.org/citations/31006538 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31006538 |
| http://purl.uniprot.org/citations/31006538 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/31006538 |
| http://purl.uniprot.org/citations/31006538 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/31006538 |
| http://purl.uniprot.org/uniprot/Q9GZQ8 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/31006538 |
| http://purl.uniprot.org/uniprot/O95166 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/31006538 |