RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/31030479http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/31030479http://www.w3.org/2000/01/rdf-schema#comment"Background: The identification of cancer-associated single nucleotide polymorphisms (SNP) and mutation genes is a promising approach in recognizing individuals who are at risk of developing cancer. Hence, this study was conducted to determine the association between XRCC4 c.1394G>T SNP and breast cancer development among Filipinos. Methods: Genotyping for XRCC4 c.1394G>T SNP was performed on breast cancer patients (n=103) and their age- and sex-matched clinically healthy controls (n=103) by polymerase chain reaction – restriction fragment length polymorphism. Results: Significant difference in genotype (p=0.007) and allele (p=0.003) frequencies in XRCC4 c.1394G>T was observed between the breast cancer cases and controls. Carriers of the XRCC4 c.1394 G>T genotype were observed to have significantly higher risk of developing breast cancer compared to individuals with T/T genotype (OR=2.67, 95% CI: 1.36 – 5.25). XRCC4 c.1394G>T combined with passive smoking may also significantly increase risk of breast cancer (OR=14.73; 95% CI= 9.88-18.86). Conclusion: XRCC4 c. 1394G>T may be associated with breast cancer development among Filipinos."xsd:string
http://purl.uniprot.org/citations/31030479http://purl.org/dc/terms/identifier"doi:10.31557/apjcp.2019.20.4.1097"xsd:string
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/author"Garcia J.A."xsd:string
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/author"Albano P.M."xsd:string
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/author"Ramos M.C."xsd:string
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/author"Kalacas N.A."xsd:string
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/author"Sy Ortin T."xsd:string
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/date"2019"xsd:gYear
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/name"Asian Pac J Cancer Prev"xsd:string
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/pages"1097-1101"xsd:string
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/title"XRCC4 c.1394G>T Single Nucleotide Polymorphisms and Breast Cancer Risk among Filipinos."xsd:string
http://purl.uniprot.org/citations/31030479http://purl.uniprot.org/core/volume"20"xsd:string
http://purl.uniprot.org/citations/31030479http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/31030479
http://purl.uniprot.org/citations/31030479http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/31030479
http://purl.uniprot.org/uniprot/#_Q7Z763-mappedCitation-31030479http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31030479
http://purl.uniprot.org/uniprot/#_Q13426-mappedCitation-31030479http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31030479
http://purl.uniprot.org/uniprot/Q13426http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/31030479
http://purl.uniprot.org/uniprot/Q7Z763http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/31030479