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http://purl.uniprot.org/citations/3108879http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3108879http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3108879http://www.w3.org/2000/01/rdf-schema#comment"Two distinct beta subunits of guanine nucleotide-binding regulatory proteins have been identified by cDNA cloning and are referred to as beta 1 and beta 2 subunits. The bovine transducin beta subunit (beta 1) has been cloned previously. We have now isolated and analyzed cDNA clones that encode the beta 2 subunit from bovine adrenal, bovine brain, and a human myeloid leukemia cell line, HL-60. The 340-residue Mr 37,329 beta 2 protein is 90% identical with beta 1 in predicted amino acid sequence, and it is also organized as a series of repetitive homologous segments. The major mRNA that encodes the bovine beta 2 subunit is 1.7 kilobases in length. It is expressed at lower levels than beta 1 subunit mRNA in all tissues examined. The beta 1 and beta 2 messages are expressed in cloned human cell lines. Hybridization of cDNA probes to bovine DNA showed that beta 1 and beta 2 are encoded by separate genes. The amino acid sequences for the bovine and human beta 2 subunit are identical, as are the amino acid sequences for the bovine and human beta 1 subunit. This evolutionary conservation suggests that the two beta subunits have different roles in the signal transduction process."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.org/dc/terms/identifier"doi:10.1073/pnas.84.11.3792"xsd:string
http://purl.uniprot.org/citations/3108879http://purl.org/dc/terms/identifier"doi:10.1073/pnas.84.11.3792"xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/author"Birren B.W."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/author"Birren B.W."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/author"Simon M.I."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/author"Simon M.I."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/author"Amatruda T.T. III"xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/author"Amatruda T.T. III"xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/author"Fong H.K.W."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/author"Fong H.K.W."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/date"1987"xsd:gYear
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/date"1987"xsd:gYear
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/pages"3792-3796"xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/pages"3792-3796"xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/title"Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/title"Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning."xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/volume"84"xsd:string
http://purl.uniprot.org/citations/3108879http://purl.uniprot.org/core/volume"84"xsd:string
http://purl.uniprot.org/citations/3108879http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3108879
http://purl.uniprot.org/citations/3108879http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/3108879