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http://purl.uniprot.org/citations/31205016http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/31205016http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/31205016http://www.w3.org/2000/01/rdf-schema#comment"The crystal structure of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) from the hyperthermophilic archaeon Hyperthermus butylicus is presented at 1.8 Å resolution. Previous structures of archaeal Rubisco have been found to assemble into decamers, and this oligomerization was thought to be required for a highly thermally stable enzyme. In the current study, H. butylicus Rubisco is shown to exist as a dimer in solution, yet has a thermal denaturation midpoint of 114°C, suggesting that high thermal stability can be achieved without an increased oligomeric state. This increased thermal stability appears to be due to an increased number of electrostatic interactions within the monomeric subunit. As such, H. butylicus Rubisco presents a well characterized system in which to investigate the role of assembly and thermal stability in enzyme function."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.org/dc/terms/identifier"doi:10.1107/S2059798319006466"xsd:string
http://purl.uniprot.org/citations/31205016http://purl.org/dc/terms/identifier"doi:10.1107/s2059798319006466"xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/author"Pearce F.G."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/author"Pearce F.G."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/author"Bundela R."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/author"Bundela R."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/author"Keown J."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/author"Keown J."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/author"Watkin S."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/author"Watkin S."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/date"2019"xsd:gYear
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/date"2019"xsd:gYear
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/name"Acta Crystallogr. D Struct. Biol."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/name"Acta Crystallogr D Struct Biol"xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/pages"536-544"xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/pages"536-544"xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/title"Structure of a hyperthermostable dimeric archaeal Rubisco from Hyperthermus butylicus."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/title"Structure of a hyperthermostable dimeric archaeal Rubisco from Hyperthermus butylicus."xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/volume"75"xsd:string
http://purl.uniprot.org/citations/31205016http://purl.uniprot.org/core/volume"75"xsd:string
http://purl.uniprot.org/citations/31205016http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/31205016
http://purl.uniprot.org/citations/31205016http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/31205016