| http://purl.uniprot.org/citations/31212927 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31212927 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31212927 | http://www.w3.org/2000/01/rdf-schema#comment | "Japanese encephalitis virus (JEV) is a zoonotic mosquito-borne flavivirus which is the leading causative agent of viral encephalitis in endemic regions. JEV NS3 is a component of the viral replicase complex and is a multifunctional protein. In this study, interleukin enhancer-binding factor 2 (ILF2) is identified as a novel cellular protein interacting with NS3 through co-immunoprecipitation assay and LC-MS/MS. The expression of ILF2 is decreased in JEV-infected human embryonic kidney (293T) cells. The knockdown of endogenous ILF2 by special short hairpin RNA (shRNA) positively regulates JEV propagation, whereas the overexpression of ILF2 results in a significantly reduced JEV genome synthesis. Further analysis revealed that the knockdown of ILF2 positively regulates viral replication by JEV replicon system studies. These results suggest that ILF2 may act as a potential antiviral agent against JEV infection."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.org/dc/terms/identifier | "doi:10.3390/v11060559"xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.org/dc/terms/identifier | "doi:10.3390/v11060559"xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Chen H."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Chen H."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Cui X."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Cui X."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Wei Y."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Wei Y."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Zhao F."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Zhao F."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Rao T."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Rao T."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Qian P."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/author | "Qian P."xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/name | "Viruses"xsd:string |
| http://purl.uniprot.org/citations/31212927 | http://purl.uniprot.org/core/name | "Viruses"xsd:string |