| http://purl.uniprot.org/citations/31243991 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31243991 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31243991 | http://www.w3.org/2000/01/rdf-schema#comment | "Division of fungal and animal cells depends on scaffold proteins called anillins. Cytokinesis by the fission yeast Schizosaccharomyces pombe is compromised by the loss of anillin Mid1p (Mid1, UniProtKB P78953 ), because cytokinesis organizing centers, called nodes, are misplaced and fail to acquire myosin-II, so they assemble slowly into abnormal contractile rings. The C-terminal half of Mid1p consists of lipid binding C2 and PH domains, but the N-terminal half (Mid1p-N452) performs most of the functions of the full-length protein. Little is known about the structure of the N-terminal half of Mid1p, so we investigated its physical properties using structure prediction tools, spectroscopic techniques, and hydrodynamic measurements. The data indicate that Mid1p-N452 is intrinsically disordered but moderately compact. Recombinant Mid1p-N452 purified from insect cells was phosphorylated, which weakens its tendency to aggregate. Purified Mid1p-N452 demixes into liquid droplets at concentrations far below its concentration in nodes. These physical properties are appropriate for scaffolding other proteins in nodes."xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.org/dc/terms/identifier | "doi:10.1021/acs.biochem.9b00217"xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.org/dc/terms/identifier | "doi:10.1021/acs.biochem.9b00217"xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/author | "Pollard T.D."xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/author | "Pollard T.D."xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/author | "Chatterjee M."xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/author | "Chatterjee M."xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/date | "2019"xsd:gYear |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/pages | "3031-3041"xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/pages | "3031-3041"xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/title | "The functionally important N-terminal half of fission yeast Mid1p anillin is intrinsically disordered and undergoes phase separation."xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/title | "The functionally important N-terminal half of fission yeast Mid1p anillin is intrinsically disordered and undergoes phase separation."xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/volume | "58"xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://purl.uniprot.org/core/volume | "58"xsd:string |
| http://purl.uniprot.org/citations/31243991 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31243991 |
| http://purl.uniprot.org/citations/31243991 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31243991 |
| http://purl.uniprot.org/citations/31243991 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/31243991 |
| http://purl.uniprot.org/citations/31243991 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/31243991 |
| http://purl.uniprot.org/uniprot/P78953 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/31243991 |
| http://purl.uniprot.org/uniprot/P78953#attribution-6481FE8DD9C85B36F0825133FF1D8A55 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/31243991 |