| http://purl.uniprot.org/citations/31335488 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31335488 | http://www.w3.org/2000/01/rdf-schema#comment | "Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX) is involved in the epigenetic regulation. A previous mouse xenograft study revealed that UTX knockdown is associated with downregulated expression of matrix metalloproteinase-11 (MMP-11). The authors investigated 224 cases of breast cancer from Kangbuk Samsung Medical Center between 2000 and 2005. Nuclear UTX and cytoplasmic MMP-11 expressions were assessed using immunohistochemistry of tumor tissue microarray specimens. The relationships between the expression of UTX, MMP-11, and patients' outcomes were analyzed. UTX expression was significantly associated with high histologic grade, lymphatic invasion, vascular invasion, and tumoral expression of MMP-11. Survival analysis revealed that patients with UTX expression had a poorer overall survival rate (P=0.010) as well as diminished disease-free survival rate (P=0.001). The prognostic power of UTX expression was significant in patients with luminal-type breast cancer (P=0.027, overall survival; P=0.008, disease-free survival). Validation of UTX can provide further prognostic information beyond traditional indicators and represents a potential therapeutic target for breast cancer."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.org/dc/terms/identifier | "doi:10.1097/pai.0000000000000795"xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/author | "Kim Y.H."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/author | "Kim S.H."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/author | "Kim D.H."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/author | "Kim G.J."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/author | "Moon K.M."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/author | "Son B.K."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/author | "Chae S.W."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/author | "Min K.W."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/name | "Appl Immunohistochem Mol Morphol"xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/pages | "544-550"xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/title | "Expression of UTX Indicates Poor Prognosis in Patients With Luminal Breast Cancer and is Associated With MMP-11 Expression."xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/31335488 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31335488 |
| http://purl.uniprot.org/citations/31335488 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/31335488 |
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| http://purl.uniprot.org/uniprot/#_B4E253-mappedCitation-31335488 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31335488 |
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