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http://purl.uniprot.org/citations/31431626http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/31431626http://www.w3.org/2000/01/rdf-schema#comment"Double-stranded DNA bacteriophages package their genome at high pressure inside a procapsid through the portal, an oligomeric ring protein located at a unique capsid vertex. Once the DNA has been packaged, the tail components assemble on the portal to render the mature infective virion. The tail tightly seals the ejection conduit until infection, when its interaction with the host membrane triggers the opening of the channel and the viral genome is delivered to the host cell. Using high-resolution cryo-electron microscopy and X-ray crystallography, here we describe various structures of the T7 bacteriophage portal and fiber-less tail complex, which suggest a possible mechanism for DNA retention and ejection: a portal closed conformation temporarily retains the genome before the tail is assembled, whereas an open portal is found in the tail. Moreover, a fold including a seven-bladed β-propeller domain is described for the nozzle tail protein."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.org/dc/terms/identifier"doi:10.1038/s41467-019-11705-9"xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Coll M."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Fernandez F.J."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Carrascosa J.L."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Cuervo A."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Vega M.C."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Pous J."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Perez-Luque R."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Perez-Ruiz M."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Conesa J.J."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Machon C."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/author"Fabrega-Ferrer M."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/date"2019"xsd:gYear
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/name"Nat Commun"xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/pages"3746"xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/title"Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism."xsd:string
http://purl.uniprot.org/citations/31431626http://purl.uniprot.org/core/volume"10"xsd:string
http://purl.uniprot.org/citations/31431626http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/31431626
http://purl.uniprot.org/citations/31431626http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/31431626
http://purl.uniprot.org/uniprot/#_P03728-mappedCitation-31431626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31431626
http://purl.uniprot.org/uniprot/#_P03746-mappedCitation-31431626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31431626
http://purl.uniprot.org/uniprot/#_P03747-mappedCitation-31431626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31431626
http://purl.uniprot.org/uniprot/P03746http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/31431626