http://purl.uniprot.org/citations/31455787 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/31455787 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/31455787 | http://www.w3.org/2000/01/rdf-schema#comment | "The RNA exosome is a key 3'-5' exoribonuclease with an evolutionarily conserved structure and function. Its cytosolic functions require the co-factors SKI7 and the Ski complex. Here we demonstrate by co-purification experiments that the ARM-repeat protein RESURRECTION1 (RST1) and RST1 INTERACTING PROTEIN (RIPR) connect the cytosolic Arabidopsis RNA exosome to the Ski complex. rst1 and ripr mutants accumulate RNA quality control siRNAs (rqc-siRNAs) produced by the post-transcriptional gene silencing (PTGS) machinery when mRNA degradation is compromised. The small RNA populations observed in rst1 and ripr mutants are also detected in mutants lacking the RRP45B/CER7 core exosome subunit. Thus, molecular and genetic evidence supports a physical and functional link between RST1, RIPR and the RNA exosome. Our data reveal the existence of additional cytosolic exosome co-factors besides the known Ski subunits. RST1 is not restricted to plants, as homologues with a similar domain architecture but unknown function exist in animals, including humans."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-019-11807-4"xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-019-11807-4"xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Hammann P."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Hammann P."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Lange H."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Lange H."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Pflieger D."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Pflieger D."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Weigel D."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Weigel D."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Kuhn L."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Kuhn L."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Vaucheret H."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Vaucheret H."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Butel N."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Butel N."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Chicher J."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Chicher J."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Christie M."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Christie M."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Gagliardi D."xsd:string |
http://purl.uniprot.org/citations/31455787 | http://purl.uniprot.org/core/author | "Gagliardi D."xsd:string |