| http://purl.uniprot.org/citations/31587070 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31587070 | http://www.w3.org/2000/01/rdf-schema#comment | "An increased concentration of cytosolic Ca2+ is an early response of plant cells to heat shock. Arabidopsis cyclic nucleotide-gated ion channel 6 (CNGC6) mediates heat-induced Ca2+ influx and is activated by cAMP. However, it remains unclear how the Ca2+ conductivity of CNGC6 is negatively regulated under the elevated cytosolic Ca2+ concentration. In this study, Arabidopsis calmodulin isoforms CaM1/4, CaM2/3/5, CaM6, and CaM7 were found to bind to CNGC6 to varying degrees, and this binding was dependent on the presence of Ca2+ and IQ6, an atypical isoleucine-glutamine motif in CNGC6. Knockout of CaM2, CaM3, CaM5, and CaM7 genes led to a marked increase in plasma membrane inward Ca2+ current under heat shock conditions; however, knockout of CaM1, CaM4, and CaM6 genes had no significant effect on plasma membrane Ca2+ current. Moreover, the deletion of IQ6 from CNGC6 led to a marked increase in plasma membrane Ca2+ current under heat shock conditions. Taken together, the data suggest that CNGC6-mediated Ca2+ influx is likely to be negatively regulated by CaM2/3/5 and CaM7 isoforms under heat shock conditions, and that IQ6 plays an important role in CaM binding and the feedback regulation of the channel."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.org/dc/terms/identifier | "doi:10.1093/jxb/erz445"xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Fan X."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Gao F."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Li B."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Wang J."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Zhang B."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Wang Z.X."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Wei S.S."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Zheng S.Z."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Yang D.W."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Shang Z.L."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Han X.W."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Bai J.T."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/author | "Niu W.T."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/name | "J Exp Bot"xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/pages | "90-104"xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/title | "Arabidopsis cyclic nucleotide-gated channel 6 is negatively modulated by multiple calmodulin isoforms during heat shock."xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://purl.uniprot.org/core/volume | "71"xsd:string |
| http://purl.uniprot.org/citations/31587070 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31587070 |
| http://purl.uniprot.org/citations/31587070 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/31587070 |
| http://purl.uniprot.org/uniprot/#_F4K8M2-mappedCitation-31587070 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31587070 |
| http://purl.uniprot.org/uniprot/#_F4K8M3-mappedCitation-31587070 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31587070 |