http://purl.uniprot.org/citations/3159820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3159820 | http://www.w3.org/2000/01/rdf-schema#comment | "In previous studies (17-21), monoclonal antibody (mAb) 9.3 has been shown to react with a major population of human T cells, which include T4+ helper/inducer T cells and T8+ cytotoxic T cells. In this investigation, mAb 9.3 was shown to precipitate a disulfide-bonded dimer of a 44 kD polypeptide. Comodulation experiments showed that this molecule is not linked to T3/Ti or T11 antigens. mAb 9.3 was capable of inducing T cell proliferation in the presence of 12-o-tetradecanoyl phorbol-13-acetate (TPA). This effect was monocyte-independent. T cell activation with mAb 9.3 and TPA was associated with increases in interleukin 2(IL-2) receptor expression and IL-2 secretion. mAb 9.3 did not activate T cells, even with the addition of IL-1 or IL-2. Modulation of the T3 complex did not abolish mAb 9.3-induced T cell proliferation in the presence of TPA. These results suggest that the 9.3 antigen may serve as a receptor for an activation pathway restricted to a T cell subset."xsd:string |
http://purl.uniprot.org/citations/3159820 | http://purl.org/dc/terms/identifier | "doi:10.1084/jem.161.6.1513"xsd:string |
http://purl.uniprot.org/citations/3159820 | http://purl.uniprot.org/core/author | "Hara T."xsd:string |
http://purl.uniprot.org/citations/3159820 | http://purl.uniprot.org/core/author | "Fu S.M."xsd:string |
http://purl.uniprot.org/citations/3159820 | http://purl.uniprot.org/core/author | "Hansen J.A."xsd:string |
http://purl.uniprot.org/citations/3159820 | http://purl.uniprot.org/core/date | "1985"xsd:gYear |
http://purl.uniprot.org/citations/3159820 | http://purl.uniprot.org/core/name | "J Exp Med"xsd:string |
http://purl.uniprot.org/citations/3159820 | http://purl.uniprot.org/core/pages | "1513-1524"xsd:string |
http://purl.uniprot.org/citations/3159820 | http://purl.uniprot.org/core/title | "Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen)."xsd:string |
http://purl.uniprot.org/citations/3159820 | http://purl.uniprot.org/core/volume | "161"xsd:string |
http://purl.uniprot.org/citations/3159820 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3159820 |
http://purl.uniprot.org/citations/3159820 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/3159820 |
http://purl.uniprot.org/uniprot/P10747#attribution-13FE3C1D02C58CCF65F2E3D7571C8933 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/3159820 |
http://purl.uniprot.org/uniprot/P10747#attribution-9336E10098CFFEBA9A8264EF32EEAB0D | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/3159820 |