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http://purl.uniprot.org/citations/31651850http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/31651850http://www.w3.org/2000/01/rdf-schema#comment"The aim of this study was to investigate the correlation between cluster of differentiation 86 (CD86) gene rs1129055 and rs2715267 single nucleotide polymorphisms and sepsis susceptibility.One hundred twenty-five sepsis patients and 120 healthy controls were enrolled in this case-control study. CD86 polymorphisms rs1129055 and rs2715267 were genotyped through polymerase chain reaction-restriction fragment length polymorphism approach. Chi-square test was used to analyze differences in genotype and allele frequencies of the 2 polymorphisms between case and control groups. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to present the association strength of the polymorphisms with sepsis susceptibility.AA genotype and A allele frequencies of CD86 rs1129055 were significantly lower in sepsis patients than in healthy controls (P < .05), revealing their significant associations with decreased disease susceptibility (OR = 0.351, 95% CI = 0.169-0.728; OR = 0.593, 95% CI = 0.415-0.847). Nevertheless, rs2715267 had no significant association with sepsis susceptibility (P > .05).AA genotype and A allele of CD86 polymorphism rs1129055 might be correlated with decreased sepsis susceptibility in Chinese Han population, but not rs2715267. Further study should be performed to verify our findings."xsd:string
http://purl.uniprot.org/citations/31651850http://purl.org/dc/terms/identifier"doi:10.1097/md.0000000000017482"xsd:string
http://purl.uniprot.org/citations/31651850http://purl.uniprot.org/core/author"Li B."xsd:string
http://purl.uniprot.org/citations/31651850http://purl.uniprot.org/core/author"Wu S."xsd:string
http://purl.uniprot.org/citations/31651850http://purl.uniprot.org/core/author"Zou X."xsd:string
http://purl.uniprot.org/citations/31651850http://purl.uniprot.org/core/author"Cai J."xsd:string
http://purl.uniprot.org/citations/31651850http://purl.uniprot.org/core/date"2019"xsd:gYear
http://purl.uniprot.org/citations/31651850http://purl.uniprot.org/core/name"Medicine (Baltimore)"xsd:string
http://purl.uniprot.org/citations/31651850http://purl.uniprot.org/core/pages"e17482"xsd:string
http://purl.uniprot.org/citations/31651850http://purl.uniprot.org/core/title"Genetic association between cluster of differentiation 86 variations and sepsis risk: A case-control study."xsd:string
http://purl.uniprot.org/citations/31651850http://purl.uniprot.org/core/volume"98"xsd:string
http://purl.uniprot.org/citations/31651850http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/31651850
http://purl.uniprot.org/citations/31651850http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/31651850
http://purl.uniprot.org/uniprot/#_A0A0X9R4E0-mappedCitation-31651850http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31651850
http://purl.uniprot.org/uniprot/#_B2R7S9-mappedCitation-31651850http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31651850
http://purl.uniprot.org/uniprot/#_A8K632-mappedCitation-31651850http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31651850
http://purl.uniprot.org/uniprot/#_P42081-mappedCitation-31651850http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31651850
http://purl.uniprot.org/uniprot/A0A0X9R4E0http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/31651850
http://purl.uniprot.org/uniprot/P42081http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/31651850
http://purl.uniprot.org/uniprot/B2R7S9http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/31651850
http://purl.uniprot.org/uniprot/A8K632http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/31651850