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http://purl.uniprot.org/citations/31693752http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/31693752http://www.w3.org/2000/01/rdf-schema#comment"Selective autophagy for the elimination of aberrant mitochondria, termed mitophagy, can be regulated by the kinase PINK1 and the ubiquitin ligase Parkin. The lysosome-associated membrane protein 2 (LAMP-2) plays diverse functions in non-selective autophagy, chaperone-mediated autophagy and selective autophagy for the degradation of RNA/DNA. In the present study, we investigated whether LAMP-2 plays important roles during PINK1/Parkin-mediated mitophagy. The results obtained clearly show that knockdown of LAMP-2 does not cause defects in mitophagy in HeLa cells stably expressing Parkin, indicating that LAMP-2 is dispensable for PINK1/Parkin-mediated mitophagy. The present study is the first to determine the potential role of LAMP-2 in PINK1/Parkin-mediated mitophagy, thereby providing more insight into the sophisticated process of mitophagy."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.org/dc/terms/identifier"doi:10.1002/1873-3468.13663"xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Chen C."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Jiang X."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Liu X."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Qin X."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Zhang J."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Wang B."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Xu G."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Liao X."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Zou Z."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/author"Rao X."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/date"2020"xsd:gYear
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/pages"823-840"xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/title"The lysosomal membrane protein LAMP-2 is dispensable for PINK1/Parkin-mediated mitophagy."xsd:string
http://purl.uniprot.org/citations/31693752http://purl.uniprot.org/core/volume"594"xsd:string
http://purl.uniprot.org/citations/31693752http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/31693752
http://purl.uniprot.org/citations/31693752http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/31693752
http://purl.uniprot.org/uniprot/#_D3JZW5-mappedCitation-31693752http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31693752
http://purl.uniprot.org/uniprot/#_D3K2X1-mappedCitation-31693752http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31693752
http://purl.uniprot.org/uniprot/#_D3K2X2-mappedCitation-31693752http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31693752
http://purl.uniprot.org/uniprot/#_A0A0S2Z446-mappedCitation-31693752http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31693752
http://purl.uniprot.org/uniprot/#_A0A0S2Z447-mappedCitation-31693752http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31693752