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http://purl.uniprot.org/citations/31702436http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/31702436http://www.w3.org/2000/01/rdf-schema#comment"Plants have evolved mechanisms to protect themselves against pathogenic microbes and insect pests. In Arabidopsis, the immune regulator PAD4 functions with its cognate partner EDS1 to limit pathogen growth. PAD4, independently of EDS1, reduces infestation by green peach aphid (GPA). How PAD4 regulates these defense outputs is unclear. By expressing the N-terminal PAD4 lipase-like domain (PAD4LLD) without its C-terminal EDS1-PAD4 (EP) domain, we interrogated PAD4 functions in plant defense. Here, we show that transgenic expression of PAD4LLD in Arabidopsis is sufficient for limiting GPA infestation but not for conferring basal and effector-triggered pathogen immunity. This suggests that the C-terminal PAD4 EP domain is necessary for EDS1-dependent immune functions but is dispensable for aphid resistance. Moreover, PAD4LLD is not sufficient to interact with EDS1, indicating the PAD4-EP domain is required for stable heterodimerization. These data provide molecular evidence that PAD4 has domain-specific functions."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.org/dc/terms/identifier"doi:10.1094/mpmi-08-19-0245-r"xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/author"Parker J.E."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/author"Patel M."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/author"Shah J."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/author"Deslandes L."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/author"Archer L."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/author"Dongus J.A."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/author"Bhandari D.D."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/author"Dijkgraaf L."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/date"2020"xsd:gYear
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/name"Mol Plant Microbe Interact"xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/pages"328-335"xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/title"The Arabidopsis PAD4 Lipase-Like Domain Is Sufficient for Resistance to Green Peach Aphid."xsd:string
http://purl.uniprot.org/citations/31702436http://purl.uniprot.org/core/volume"33"xsd:string
http://purl.uniprot.org/citations/31702436http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/31702436
http://purl.uniprot.org/citations/31702436http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/31702436
http://purl.uniprot.org/uniprot/#_Q9S745-mappedCitation-31702436http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31702436
http://purl.uniprot.org/uniprot/#_Q9SU72-mappedCitation-31702436http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/31702436
http://purl.uniprot.org/uniprot/Q9SU72http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/31702436
http://purl.uniprot.org/uniprot/Q9S745http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/31702436