http://purl.uniprot.org/citations/31841145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/31841145 | http://www.w3.org/2000/01/rdf-schema#comment | "During centriole duplication, a preprocentriole forms at a single site on the mother centriole through a process that includes the hierarchical recruitment of a conserved set of proteins, including the Polo-like kinase 4 (Plk4), Ana2/STIL, and the cartwheel protein Sas6. Ana2/STIL is critical for procentriole assembly, and its recruitment is controlled by the kinase activity of Plk4, but how this works remains poorly understood. A structural motif called the G-box in the centriole outer wall protein Sas4 interacts with a short region in the N terminus of Ana2/STIL. Here, we show that binding of Ana2 to the Sas4 G-box enables hyperphosphorylation of the Ana2 N terminus by Plk4. Hyperphosphorylation increases the affinity of the Ana2-G-box interaction, and, consequently, promotes the accumulation of Ana2 at the procentriole to induce daughter centriole formation."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.201905172"xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/author | "Rusan N.M."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/author | "Buster D.W."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/author | "Galletta B.J."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/author | "Rogers G.C."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/author | "Fagerstrom C.J."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/author | "McLamarrah T.A."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/author | "Ryniawec J.M."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/author | "Speed S.K."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/name | "J Cell Biol"xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/pages | "e201905172"xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/title | "A molecular mechanism for the procentriole recruitment of Ana2."xsd:string |
http://purl.uniprot.org/citations/31841145 | http://purl.uniprot.org/core/volume | "219"xsd:string |
http://purl.uniprot.org/citations/31841145 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31841145 |
http://purl.uniprot.org/citations/31841145 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/31841145 |
http://purl.uniprot.org/uniprot/#_A0A0B4K6Z9-mappedCitation-31841145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31841145 |
http://purl.uniprot.org/uniprot/#_A0A0B4K863-mappedCitation-31841145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31841145 |
http://purl.uniprot.org/uniprot/#_A0A0B4K773-mappedCitation-31841145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31841145 |
http://purl.uniprot.org/uniprot/#_A0A0B4K7N9-mappedCitation-31841145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31841145 |
http://purl.uniprot.org/uniprot/#_A0A0B4LFU9-mappedCitation-31841145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31841145 |
http://purl.uniprot.org/uniprot/#_A1Z9D3-mappedCitation-31841145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31841145 |
http://purl.uniprot.org/uniprot/#_A1Z9D4-mappedCitation-31841145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31841145 |