http://purl.uniprot.org/citations/31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/31873307 | http://www.w3.org/2000/01/rdf-schema#comment | "The bacterial ribosome is recycled into subunits by two conserved proteins, elongation factor G (EF-G) and the ribosome recycling factor (RRF). The molecular basis for ribosome recycling by RRF and EF-G remains unclear. Here, we report the crystal structure of a posttermination Thermus thermophilus 70S ribosome complexed with EF-G, RRF and two transfer RNAs at a resolution of 3.5 Å. The deacylated tRNA in the peptidyl (P) site moves into a previously unsuspected state of binding (peptidyl/recycling, p/R) that is analogous to that seen during initiation. The terminal end of the p/R-tRNA forms nonfavorable contacts with the 50S subunit while RRF wedges next to central inter-subunit bridges, illuminating the active roles of tRNA and RRF in dissociation of ribosomal subunits. The structure uncovers a missing snapshot of tRNA as it transits between the P and exit (E) sites, providing insights into the mechanisms of ribosome recycling and tRNA translocation."xsd:string |
http://purl.uniprot.org/citations/31873307 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41594-019-0350-7"xsd:string |
http://purl.uniprot.org/citations/31873307 | http://purl.uniprot.org/core/author | "Lin J."xsd:string |
http://purl.uniprot.org/citations/31873307 | http://purl.uniprot.org/core/author | "Zhou D."xsd:string |
http://purl.uniprot.org/citations/31873307 | http://purl.uniprot.org/core/author | "Gagnon M.G."xsd:string |
http://purl.uniprot.org/citations/31873307 | http://purl.uniprot.org/core/author | "Tanzawa T."xsd:string |
http://purl.uniprot.org/citations/31873307 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
http://purl.uniprot.org/citations/31873307 | http://purl.uniprot.org/core/name | "Nat Struct Mol Biol"xsd:string |
http://purl.uniprot.org/citations/31873307 | http://purl.uniprot.org/core/pages | "25-32"xsd:string |
http://purl.uniprot.org/citations/31873307 | http://purl.uniprot.org/core/title | "Structural basis for ribosome recycling by RRF and tRNA."xsd:string |
http://purl.uniprot.org/citations/31873307 | http://purl.uniprot.org/core/volume | "27"xsd:string |
http://purl.uniprot.org/citations/31873307 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31873307 |
http://purl.uniprot.org/citations/31873307 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/31873307 |
http://purl.uniprot.org/uniprot/#_P35871-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P0DOY6-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P0DOY7-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P0DOY8-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P0DOY9-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P17291-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P80339-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P80340-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P80371-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P80372-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |
http://purl.uniprot.org/uniprot/#_P80373-mappedCitation-31873307 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31873307 |