| http://purl.uniprot.org/citations/31876620 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31876620 | http://www.w3.org/2000/01/rdf-schema#comment | "Our aim was to investigate whether polymorphisms in the interleukin-4 (IL-4) gene are associated with the risk of colorectal cancer (CRC) in a Chinese Han population. Six single-nucleotide polymorphisms (SNPs) in the IL-4 were genotyped by Agena MassARRAY in 248 CRC patients and 463 healthy controls. The association of IL-4 polymorphisms with CRC risk was assessed by genetic models, linkage disequilibrium, and haplotype analyses. The results suggested that the CC genotype of rs2243250 confers a lower risk of CRC in the recessive model [odds ratio (OR) = 0.42, 95% confidence interval (CI): 0.19-0.92, P = 0.020]. Similarly, rs2227284 GG was associated with a reduced risk of CRC in the codominant (OR = 0.18, 95% CI: 0.04-0.82, P = 0.027) and recessive (OR = 0.19, 95% CI: 0.04-0.83, P = 0.008) models adjusted for age. Our findings suggested that rs2243250 and rs2227284 in IL-4 are associated significantly with reduced CRC risk, which may facilitate the identification of CRC patients in Chinese populations."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.org/dc/terms/identifier | "doi:10.1097/cej.0000000000000503"xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/author | "Guo Y."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/author | "Liu F."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/author | "Wen X."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/author | "Wang R."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/author | "Xin X."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/author | "Qu Z."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/author | "Qiao L."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/name | "Eur J Cancer Prev"xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/pages | "95-99"xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/title | "The correlation between IL-4 polymorphisms and colorectal cancer risk in a population in Northwest China."xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://purl.uniprot.org/core/volume | "29"xsd:string |
| http://purl.uniprot.org/citations/31876620 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31876620 |
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| http://purl.uniprot.org/uniprot/#_P05112-mappedCitation-31876620 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31876620 |
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