| http://purl.uniprot.org/citations/31939740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/31939740 | http://www.w3.org/2000/01/rdf-schema#comment | "SynGAP is a postsynaptic density (PSD) protein that binds to PDZ domains of the scaffold protein PSD-95. We previously reported that heterozygous deletion of Syngap1 in mice is correlated with increased steady-state levels of other key PSD proteins that bind PSD-95, although the level of PSD-95 remains constant (Walkup et al., 2016). For example, the ratio to PSD-95 of Transmembrane AMPA-Receptor-associated Proteins (TARPs), which mediate binding of AMPA-type glutamate receptors to PSD-95, was increased in young Syngap1+/-mice. Here we show that only females and not males show a highly significant correlation between an increase in TARP and a decrease in synGAP in the PSDs of Syngap1+/-rodents. The data reveal a sex difference in the adaptation of the PSD scaffold to synGAP haploinsufficiency."xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.org/dc/terms/identifier | "doi:10.7554/elife.52656"xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/author | "Basu S."xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/author | "Kennedy M.B."xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/author | "Kind P.C."xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/author | "Chattarji S."xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/author | "Till S.M."xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/author | "Mastro T.L."xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/author | "Preza A."xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/name | "Elife"xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/pages | "e52656"xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/title | "A sex difference in the response of the rodent postsynaptic density to synGAP haploinsufficiency."xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/31939740 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/31939740 |
| http://purl.uniprot.org/citations/31939740 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/31939740 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YVS6-mappedCitation-31939740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31939740 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YUM2-mappedCitation-31939740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31939740 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YUY7-mappedCitation-31939740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31939740 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YUZ2-mappedCitation-31939740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31939740 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YUZ5-mappedCitation-31939740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31939740 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YV63-mappedCitation-31939740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31939740 |
| http://purl.uniprot.org/uniprot/#_A0A2S1B6B8-mappedCitation-31939740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31939740 |
| http://purl.uniprot.org/uniprot/#_A0A2S1B6F9-mappedCitation-31939740 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/31939740 |