| http://purl.uniprot.org/citations/32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/32125273 | http://www.w3.org/2000/01/rdf-schema#comment | "Regulation of AMPA receptor (AMPAR) expression is central to synaptic plasticity and brain function, but how these changes occur in vivo remains elusive. Here, we developed a method to longitudinally monitor the expression of synaptic AMPARs across multiple cortical layers in awake mice using two-photon imaging. We observed that baseline AMPAR expression in individual spines is highly dynamic with more dynamics in primary visual cortex (V1) layer 2/3 (L2/3) neurons than V1 L5 neurons. Visual deprivation through binocular enucleation induces a synapse-specific and depth-dependent change of synaptic AMPARs in V1 L2/3 neurons, wherein deep synapses are potentiated more than superficial synapses. The increase is specific to L2/3 neurons and absent on apical dendrites of L5 neurons, and is dependent on expression of the AMPAR-binding protein GRIP1. Our study demonstrates that specific neuronal connections, across cortical layers and even within individual neurons, respond uniquely to changes in sensory experience."xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.org/dc/terms/identifier | "doi:10.7554/elife.52420"xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/author | "Huganir R.L."xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/author | "Graves A.R."xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/author | "Tan H.L."xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/author | "Roth R.H."xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/author | "Cudmore R.H."xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/name | "Elife"xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/pages | "e52420"xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/title | "Lamina-specific AMPA receptor dynamics following visual deprivation in vivo."xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/32125273 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32125273 |
| http://purl.uniprot.org/citations/32125273 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32125273 |
| http://purl.uniprot.org/uniprot/#_D3YWY4-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |
| http://purl.uniprot.org/uniprot/#_A0A571BG81-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |
| http://purl.uniprot.org/uniprot/#_A0A8I4SX76-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |
| http://purl.uniprot.org/uniprot/#_D3Z6R6-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |
| http://purl.uniprot.org/uniprot/#_D3Z6T4-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |
| http://purl.uniprot.org/uniprot/#_D3YZL8-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |
| http://purl.uniprot.org/uniprot/#_D3Z066-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |
| http://purl.uniprot.org/uniprot/#_H7BX09-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |
| http://purl.uniprot.org/uniprot/#_H7BX90-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |
| http://purl.uniprot.org/uniprot/#_Q6GQT7-mappedCitation-32125273 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32125273 |