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http://purl.uniprot.org/citations/3219361http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3219361http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/3219361http://www.w3.org/2000/01/rdf-schema#comment"The primary structure of the ribonuclease inhibitor from pig liver has been determined by amino acid sequence analysis. The N alpha-acetylated polypeptide chain of 456 amino acids consists of 15 homologous leucine-rich repeats, characterized by leucyl residues at constant positions. Two types of alternating repeats occur, 29 (A) and 28 (B) residues long. The degree of identity between repeats of a given type ranged from 25 to 60%. Only one deletion in the B-repeat was necessary to perfectly align the leucyl residues between the two repeats. Leucine-rich repeats have previously been found in four membrane-bound proteins and one extracellular protein, and their amphiphilic character suggested that they could be involved in membrane binding. Ribonuclease inhibitor is the first example of a cytoplasmic protein containing this type of repeat. It seems likely, therefore, that leucine-rich repeats can have functions other than forming membrane binding structures."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.org/dc/terms/identifier"doi:10.1021/bi00423a006"xsd:string
http://purl.uniprot.org/citations/3219361http://purl.org/dc/terms/identifier"doi:10.1021/bi00423a006"xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Hemmings B.A."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Hemmings B.A."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Hofsteenge J."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Hofsteenge J."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Matthies R."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Matthies R."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Stone S.R."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Stone S.R."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Kieffer B."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/author"Kieffer B."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/date"1988"xsd:gYear
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/date"1988"xsd:gYear
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/name"Biochemistry"xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/name"Biochemistry"xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/pages"8537-8544"xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/pages"8537-8544"xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/title"Amino acid sequence of the ribonuclease inhibitor from porcine liver reveals the presence of leucine-rich repeats."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/title"Amino acid sequence of the ribonuclease inhibitor from porcine liver reveals the presence of leucine-rich repeats."xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/volume"27"xsd:string
http://purl.uniprot.org/citations/3219361http://purl.uniprot.org/core/volume"27"xsd:string