| http://purl.uniprot.org/citations/32203412 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/32203412 | http://www.w3.org/2000/01/rdf-schema#comment | "Potato virus X (PVX) is a positive-sense single-stranded RNA (ssRNA) filamentous plant virus belonging to the Alphaflexiviridae family, considered in recent years as a tool for nanotechnology applications. We present the cryo-electron microscopy structure of the PVX particle at a resolution of 2.2 Å. The well-defined density of the coat proteins and of the genomic RNA allowed a detailed analysis of protein-RNA interactions, including those mediated by solvent molecules. The particle is formed by repeated segments made of 8.8 coat proteins, forming a left-handed helical structure. The RNA runs in an internal crevice along the virion, packaged in 5-nucleotide repeats in which the first four bases are stacked in the classical way, while the fifth is rotated and nearly perpendicular. The resolution of the structure described here suggests a mechanism for the virion assembly and potentially provides a platform for the rational design of antiviral compounds and for the use of PVX in nanotechnology."xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41589-020-0502-4"xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/author | "Zanotti G."xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/author | "Betti C."xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/author | "Kandiah E."xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/author | "Grinzato A."xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/author | "Baschieri S."xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/author | "Lico C."xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/name | "Nat Chem Biol"xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/pages | "564-569"xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/title | "Atomic structure of potato virus X, the prototype of the Alphaflexiviridae family."xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/32203412 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32203412 |
| http://purl.uniprot.org/citations/32203412 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32203412 |
| http://purl.uniprot.org/uniprot/#_P17782-mappedCitation-32203412 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32203412 |
| http://purl.uniprot.org/uniprot/P17782 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32203412 |