| http://purl.uniprot.org/citations/32234500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/32234500 | http://www.w3.org/2000/01/rdf-schema#comment | "The Arabidopsis immune receptors RPS4 and RRS1 interact to co-confer responsiveness to bacterial effectors. The RRS1-R allele, with RPS4, responds to AvrRps4 and PopP2, whereas RRS1-S responds only to AvrRps4. Here, we show that the C terminus of RRS1-R but not RRS1-S is phosphorylated. Phosphorylation at Thr1214 in the WRKY domain maintains RRS1-R in its inactive state and also inhibits acetylation of RRS1-R by PopP2. PopP2 in turn catalyzes O-acetylation at the same site, thereby preventing its phosphorylation. Phosphorylation at other sites is required for PopP2 but not AvrRps4 responsiveness and facilitates the interaction of RRS1's C terminus with its TIR domain. Derepression of RRS1-R or RRS1-S involves effector-triggered proximity between their TIR domain and C termini. This effector-promoted interaction between these domains relieves inhibition of TIRRPS4 by TIRRRS1. Our data reveal effector-triggered and phosphorylation-regulated conformational changes within RRS1 that results in distinct modes of derepression of the complex by PopP2 and AvrRps4."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.chom.2020.03.008"xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/author | "Huang J."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/author | "Jones J.D.G."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/author | "Guo H."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/author | "Ma Y."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/author | "Sklenar J."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/author | "Ding P."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/author | "Menke F.L.H."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/author | "Ahn H.K."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/name | "Cell Host Microbe"xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/pages | "769-781.e6"xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/title | "Phosphorylation-Regulated Activation of the Arabidopsis RRS1-R/RPS4 Immune Receptor Complex Reveals Two Distinct Effector Recognition Mechanisms."xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://purl.uniprot.org/core/volume | "27"xsd:string |
| http://purl.uniprot.org/citations/32234500 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32234500 |
| http://purl.uniprot.org/citations/32234500 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32234500 |
| http://purl.uniprot.org/uniprot/#_E1B328-mappedCitation-32234500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32234500 |
| http://purl.uniprot.org/uniprot/#_P0DKH5-mappedCitation-32234500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32234500 |
| http://purl.uniprot.org/uniprot/#_Q9XGM3-mappedCitation-32234500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32234500 |
| http://purl.uniprot.org/uniprot/Q9XGM3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32234500 |
| http://purl.uniprot.org/uniprot/P0DKH5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32234500 |
| http://purl.uniprot.org/uniprot/E1B328 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32234500 |