http://purl.uniprot.org/citations/32245342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/32245342 | http://www.w3.org/2000/01/rdf-schema#comment | "Objectives: FOSL1 is overexpressed in multiple cancers including malignant glioma and contributes to different cellular processes. However, little attention has been paid to the lower grade glioma (LGG).Methods: Cox coefficients were examined to compare FOSL1 expression among different tumors types using OncoLnc. The UCSC Xena browser was used to generate Kaplan-Meier survival curves and explore the association between FOSL1 expression and overall survival (OS) in TCGA-LGG and subgroups.Results: FOSL1 expression in LGG was ranked first among 21 different cancers. LGG with lower FOSL1 expression had longer OS (P < 0.001). The astrocytoma group had the highest FOSL1 expression and shortest OS, followed by oligoastrocytoma and oligodendroglioma (P < 0.05). The 1p19q co-deletion or IDH mutation subgroups had lower FOSL1 expression and longer OS (P < 0.001). Compared with the corresponding groups, LGG with lower FOSL1 expression had longer OS than the following groups: astrocytoma, oligodendroglioma, with/without 1p19q co-deletion, with IDH mutation, with radiation, and with pharmaceutical therapy (P < 0.05).Discussion: FOSL1 is a prognostic marker in LGG and subgroups."xsd:string |
http://purl.uniprot.org/citations/32245342 | http://purl.org/dc/terms/identifier | "doi:10.1080/01616412.2020.1748323"xsd:string |
http://purl.uniprot.org/citations/32245342 | http://purl.uniprot.org/core/author | "Zhu J."xsd:string |
http://purl.uniprot.org/citations/32245342 | http://purl.uniprot.org/core/author | "Zhang Y.Q."xsd:string |
http://purl.uniprot.org/citations/32245342 | http://purl.uniprot.org/core/author | "Zhao Y.P."xsd:string |
http://purl.uniprot.org/citations/32245342 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
http://purl.uniprot.org/citations/32245342 | http://purl.uniprot.org/core/name | "Neurol Res"xsd:string |
http://purl.uniprot.org/citations/32245342 | http://purl.uniprot.org/core/pages | "522-527"xsd:string |
http://purl.uniprot.org/citations/32245342 | http://purl.uniprot.org/core/title | "Low expression of FOSL1 is associated with favorable prognosis and sensitivity to radiation/pharmaceutical therapy in lower grade glioma."xsd:string |
http://purl.uniprot.org/citations/32245342 | http://purl.uniprot.org/core/volume | "42"xsd:string |
http://purl.uniprot.org/citations/32245342 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32245342 |
http://purl.uniprot.org/citations/32245342 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32245342 |
http://purl.uniprot.org/uniprot/#_Q12952-mappedCitation-32245342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32245342 |
http://purl.uniprot.org/uniprot/#_Q498Y4-mappedCitation-32245342 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32245342 |
http://purl.uniprot.org/uniprot/Q498Y4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32245342 |
http://purl.uniprot.org/uniprot/Q12952 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32245342 |