| http://purl.uniprot.org/citations/3224808 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3224808 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3224808 | http://www.w3.org/2000/01/rdf-schema#comment | "The nucleotide sequence of the Adh region of Drosophila mojavensis has been completed and the region found to contain a pseudogene, Adh-2 and Adh-1 arranged in that order. Comparison of the sequence divergence of these genes to one another and to the Adh region of Drosophila mulleri and other species has allowed the development of a model for the evolution of the duplication of the Adh genes. There have been two major events. An initial duplication of an Adh gene whose dual promoter structure was similar to Drosophila melanogaster, resulted in a species with two Adh genes, one of which may have had only a proximal promoter. A second duplication of this gene generated an Adh region containing three genes. It is proposed that one of these is the ancestral gene having dual promoters, while the other two possess only proximal promoters. Subsequent events have resulted in both a change in the regulation of Adh-2 such that it is expressed as if it had a "distal" type promoter and the mutational inactivation of the most upstream gene resulting in the creation of a pseudogene. The sequence of the D. mojavensis Adh region has also revealed the presence of an element which is composed of juxtaposed inverted imperfectly repeated elements. There is a surprising and not fully explainable strong similarity of the nucleotide sequence of the 5' flanking region of the pseudogene in D. mojavensis and D. mulleri."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/120.3.713"xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/120.3.713"xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/author | "Atkinson P.W."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/author | "Atkinson P.W."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/author | "Mills L.E."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/author | "Mills L.E."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/author | "Starmer W.T."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/author | "Starmer W.T."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/author | "Sullivan D.T."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/author | "Sullivan D.T."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/pages | "713-723"xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/pages | "713-723"xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/title | "Structure and evolution of the Adh genes of Drosophila mojavensis."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/title | "Structure and evolution of the Adh genes of Drosophila mojavensis."xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/volume | "120"xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://purl.uniprot.org/core/volume | "120"xsd:string |
| http://purl.uniprot.org/citations/3224808 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3224808 |
| http://purl.uniprot.org/citations/3224808 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3224808 |