http://purl.uniprot.org/citations/32348677 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/32348677 | http://www.w3.org/2000/01/rdf-schema#comment | "The organization of the normal airway mucus system differs in small experimental animals from that in humans and large mammals. To address normal murine airway mucociliary clearance, Alcian blue-stained mucus transport was measured ex vivo on tracheal tissues of naïve C57BL/6, Muc5b-/-, Muc5ac-/-, and EGFP-tagged Muc5b reporter mice. Close to the larynx with a few submucosal glands, the mucus appeared as thick bundles. More distally in the trachea and in large bronchi, Alcian blue-stained mucus was organized in cloud-like formations based on the Muc5b mucin. On tilted tissue, the mucus clouds moved upward toward the larynx with an average velocity of 12 µm/s compared with 20 µm/s for beads not associated with clouds. In Muc5ac-/- mice, Muc5b formed mucus strands attached to the tissue surface, while in Muc5b-/- mice, Muc5ac had a more variable appearance. The normal mouse lung mucus thus appears as discontinuous clouds, clearly different from the stagnant mucus layer in diseased lungs."xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.org/dc/terms/identifier | "doi:10.1152/ajplung.00485.2019"xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/author | "Trillo-Muyo S."xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/author | "Evans C.M."xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/author | "Hansson G.C."xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/author | "Ermund A."xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/author | "Rodriguez-Pineiro A.M."xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/author | "Fakih D."xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/name | "Am J Physiol Lung Cell Mol Physiol"xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/pages | "L1270-L1279"xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/title | "Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin."xsd:string |
http://purl.uniprot.org/citations/32348677 | http://purl.uniprot.org/core/volume | "318"xsd:string |
http://purl.uniprot.org/citations/32348677 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32348677 |
http://purl.uniprot.org/citations/32348677 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32348677 |
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http://purl.uniprot.org/uniprot/#_E9QAQ8-mappedCitation-32348677 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32348677 |
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http://purl.uniprot.org/uniprot/#_Q8K1G6-mappedCitation-32348677 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32348677 |
http://purl.uniprot.org/uniprot/#_Q91ZX5-mappedCitation-32348677 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32348677 |
http://purl.uniprot.org/uniprot/#_Q61916-mappedCitation-32348677 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32348677 |
http://purl.uniprot.org/uniprot/#_Q9CV93-mappedCitation-32348677 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32348677 |
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