| http://purl.uniprot.org/citations/32371546 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/32371546 | http://www.w3.org/2000/01/rdf-schema#comment | "The Arabidopsis (Arabidopsis thaliana) root epidermis consists of a position-dependent pattern of root hair cells and non-hair cells. Underlying this cell type patterning is a network of transcription factors including a central MYB-basic helix-loop-helix-WD40 complex containing WEREWOLF (WER), GLABRA3 (GL3)/ENHANCER OF GLABRA3, and TRANSPARENT TESTA GLABRA1. In this study, we used a genetic enhancer screen to identify apum23-4, a mutant allele of the ribosome biogenesis factor (RBF) gene ARABIDOPSIS PUMILIO23 (APUM23), which caused prospective root hair cells to instead adopt the non-hair cell fate. We discovered that this cell fate switch relied on MYB23, a MYB protein encoded by a WER target gene and acting redundantly with WER. In the apum23-4 mutant, MYB23 exhibited ectopic expression that was WER independent and instead required ANAC082, a recently identified ribosomal stress response mediator. We examined additional RBF mutants that produced ectopic non-hair cells and determined that this cell fate switch is generally linked to defects in ribosome biogenesis. Furthermore, the flagellin peptide flg22 triggers the ANAC082-MYB23-GL2 pathway. Taken together, our study provides a molecular explanation for root epidermal cell fate switch in response to ribosomal defects and, more generally, it demonstrates a novel regulatory connection between stress conditions and cell fate control in plants."xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.org/dc/terms/identifier | "doi:10.1105/tpc.19.00773"xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/author | "Ryu K.H."xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/author | "Wang W."xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/author | "Schiefelbein J."xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/author | "Bruex A."xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/author | "Barron C."xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/name | "Plant Cell"xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/pages | "2402-2423"xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/title | "Molecular Basis for a Cell Fate Switch in Response to Impaired Ribosome Biogenesis in the Arabidopsis Root Epidermis."xsd:string |
| http://purl.uniprot.org/citations/32371546 | http://purl.uniprot.org/core/volume | "32"xsd:string |
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