http://purl.uniprot.org/citations/32376910 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/32376910 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/32376910 | http://www.w3.org/2000/01/rdf-schema#comment | "The nuclear pore complex (NPC) exhibits structural plasticity and has only been characterized at local resolutions of up to 15 Å for the cytoplasmic ring (CR). Here we present a single-particle cryo-electron microscopy (cryo-EM) structure of the CR from Xenopus laevis NPC at average resolutions of 5.5-7.9 Å, with local resolutions reaching 4.5 Å. Improved resolutions allow identification and placement of secondary structural elements in the majority of the CR components. The two Y complexes in each CR subunit interact with each other and associate with those from flanking subunits, forming a circular scaffold. Within each CR subunit, the Nup358-containing region wraps around the stems of both Y complexes, likely stabilizing the scaffold. Nup205 connects the short arms of the two Y complexes and associates with the stem of a neighboring Y complex. The Nup214-containing region uses an extended coiled-coil to link Nup85 of the two Y complexes and protrudes into the axial pore of the NPC. These previously uncharacterized structural features reveal insights into NPC assembly."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41422-020-0319-4"xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41422-020-0319-4"xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Huang G."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Huang G."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Liu M."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Liu M."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Shi Y."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Shi Y."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Wang Q."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Wang Q."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Zhu X."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Zhu X."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Tao Q."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Tao Q."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Zhou Q."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Zhou Q."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Zeng C."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Zeng C."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Lei J."xsd:string |
http://purl.uniprot.org/citations/32376910 | http://purl.uniprot.org/core/author | "Lei J."xsd:string |