Results

RDF/XMLNTriplesTurtleShow queryShare ▶
SubjectPredicateObject
http://purl.uniprot.org/citations/32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/32450701http://www.w3.org/2000/01/rdf-schema#comment"

Objective

the aim of this study was to investigate the expression of integrin αvβ6 in normal, hepatitis B, HBV-associated cirrhosis and HBV-associated HCC liver tissues.

Methods

immunohistochemistry and real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR) were used to study the expression of integrin αvβ6 in HBV-associated cirrhosis (n = 88), chronic hepatitis B ( n= 11), HBV-associated HCC (n = 84) and normal (n = 10) human liver tissues.

Results

the expression of integrin αvβ6 was significantly upregulated in HBV-associated liver cirrhosis and the expression increased with an increase in severity of cirrhosis. Furthermore, it was moderately or weakly expressed in chronic hepatitis B and HBV-associated HCC liver tissues when compared to normal liver tissue.

Conclusion

integrin αvβ6 could be a predictive marker for the progression of liver cirrhosis associated with HBV infection. Further studies are needed to determine the association between the expression of integrin αvβ6 in hepatitis B and HBV-associated HCC liver tissues."xsd:string
http://purl.uniprot.org/citations/32450701http://purl.org/dc/terms/identifier"doi:10.17235/reed.2020.6607/2019"xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/author"Gao C."xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/author"Niu J."xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/author"Peng C."xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/author"Gao H.J."xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/author"He Z.B."xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/author"Niu W.B."xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/date"2020"xsd:gYear
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/name"Rev Esp Enferm Dig"xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/pages"462-466"xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/title"The relationship between integrin avss6 and HBV infection in patients with liver cirrhosis and hepatocellular carcinoma: a preliminary report."xsd:string
http://purl.uniprot.org/citations/32450701http://purl.uniprot.org/core/volume"112"xsd:string
http://purl.uniprot.org/citations/32450701http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/32450701
http://purl.uniprot.org/citations/32450701http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/32450701
http://purl.uniprot.org/uniprot/#_A0A087WXP3-mappedCitation-32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32450701
http://purl.uniprot.org/uniprot/#_A8K2N5-mappedCitation-32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32450701
http://purl.uniprot.org/uniprot/#_E9PEE8-mappedCitation-32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32450701
http://purl.uniprot.org/uniprot/#_B4DYQ7-mappedCitation-32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32450701
http://purl.uniprot.org/uniprot/#_B4E2B8-mappedCitation-32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32450701
http://purl.uniprot.org/uniprot/#_A5YM53-mappedCitation-32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32450701
http://purl.uniprot.org/uniprot/#_P18564-mappedCitation-32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32450701
http://purl.uniprot.org/uniprot/#_L7RXH0-mappedCitation-32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32450701
http://purl.uniprot.org/uniprot/#_P06756-mappedCitation-32450701http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32450701
▶