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http://purl.uniprot.org/citations/32466705http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/32466705http://www.w3.org/2000/01/rdf-schema#comment"

Objectives.

With targeted agents, characterizing carcinomas of the gastrointestinal (GI) tract has become more important. We aim to determine the usefulness of p40 in classifying GI tract carcinomas.

Methods.

Seventy-five GI carcinomas including 28 squamous cell carcinomas (SCC), 2 adenosquamous carcinomas (ASCA), 21 poorly differentiated carcinomas (PDCA), and 24 adenocarcinomas (AdCA; control group) were stained for p40, p63, and CK5/6. Tumors were scored from 0 to 5 based on extent of staining and marked as positive (score >2) or negative.

Results.

p63 was positive in 100% of SCC/ASCA and 12.5% of AdCA. p40 was positive in 92.5% of SCC/ASCA and 4.1% of AdCA. In the PDCA subset, a panel including p63, p40, and MOC31 was the best way to accurately classify most cases.

Conclusions.

p63 and CK5/6 are more sensitive but less specific than p40 for SCC/ASCA in GI carcinomas. In PDCA, a panel approach including p63, CK5/6, and p40 may be best in classifying these cases."xsd:string
http://purl.uniprot.org/citations/32466705http://purl.org/dc/terms/identifier"doi:10.1177/1066896920924821"xsd:string
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/author"Liu X."xsd:string
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/author"Brown K.B."xsd:string
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/author"Gordon I.O."xsd:string
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/author"Allende D.S."xsd:string
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/author"Bakhshwin A.M."xsd:string
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/date"2020"xsd:gYear
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/name"Int J Surg Pathol"xsd:string
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/pages"835-843"xsd:string
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/title"Head-to-Head Comparison of p63 and p40 in Non-Neuroendocrine Carcinomas of the Tubal Gut."xsd:string
http://purl.uniprot.org/citations/32466705http://purl.uniprot.org/core/volume"28"xsd:string
http://purl.uniprot.org/citations/32466705http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/32466705
http://purl.uniprot.org/citations/32466705http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/32466705
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