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http://purl.uniprot.org/citations/32565733http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/32565733http://www.w3.org/2000/01/rdf-schema#comment"Accumulating studies have suggested the dysregulated microRNAs (miRNAs) play important roles in brain tumors, including glioma. miR-6869-5p has been documented to be aberrantly expressed in diverse cancers. However, the precise role of miR-6869-5p in glioma remains poorly understood. This study is aimed at evaluating its modifying effects on glioma. Significantly decreased expression of miR-6869-5p was found in glioma tissues and cells. Negative association was documented between miR-6869-5p and PGK1 in glioma cells, and PGK1 was demonstrated to be a targeted gene of this miRNA by luciferase reporter assay. miR-6869-5p regulated glioma cell proliferation and invasion via targeting PGK1. In addition, the survival analysis had suggested that low miR-6869-5p expression predicted poor prognosis of glioma patients. This study has suggested that miR-6869-5p is a useful tumor suppressor and prognostic marker in glioma."xsd:string
http://purl.uniprot.org/citations/32565733http://purl.org/dc/terms/identifier"doi:10.1155/2020/9752372"xsd:string
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/author"Liu B."xsd:string
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/author"Liu W."xsd:string
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/author"Zhang Z."xsd:string
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/author"Zhang H."xsd:string
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/author"Wang F."xsd:string
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/date"2020"xsd:gYear
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/name"Mediators Inflamm"xsd:string
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/pages"9752372"xsd:string
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/title"miR-6869-5p Inhibits Glioma Cell Proliferation and Invasion via Targeting PGK1."xsd:string
http://purl.uniprot.org/citations/32565733http://purl.uniprot.org/core/volume"2020"xsd:string
http://purl.uniprot.org/citations/32565733http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/32565733
http://purl.uniprot.org/citations/32565733http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/32565733
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http://purl.uniprot.org/uniprot/#_Q16444-mappedCitation-32565733http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32565733
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http://purl.uniprot.org/uniprot/B4E1H9http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/32565733