| http://purl.uniprot.org/citations/32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/32730638 | http://www.w3.org/2000/01/rdf-schema#comment | "Fibrillins (FBNs) form mesh-like structures of microfibrils in various elastic tissues. RECK and FBN1 are co-expressed in many human tissues, suggesting a functional relationship. We found that dermal FBN1 fibers show atypical morphology in mice with reduced RECK expression (RECK-Hypo mice). Dermal FBN1 fibers in mice-lacking membrane-type 1-matrix metalloproteinase (MT1-MMP) show a similar atypical morphology, despite the current notion that MT1-MMP (a membrane-bound protease) and RECK (a membrane-bound protease inhibitor) have opposing functions. Our experiments using dermal fibroblasts indicated that RECK promotes pro-MT1-MMP activation, increases cell-associated gelatinase/collagenase activity, and decreases diffusible gelatinase/collagenase activity, while MT1-MMP stabilizes RECK in these cells. Experiments using purified proteins indicate that RECK and its binding partner ADAMTS10 keep the proteolytic activity of MT1-MMP within a certain range. These findings suggest that RECK, ADAMTS10, and MT1-MMP cooperate to support the formation of robust FBN1 fibers."xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://purl.org/dc/terms/identifier | "doi:10.1002/jcp.29982"xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://purl.uniprot.org/core/author | "Noda M."xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://purl.uniprot.org/core/author | "Matsuzaki T."xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://purl.uniprot.org/core/author | "Keene D.R."xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://purl.uniprot.org/core/author | "Nishimoto E."xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/32730638 | http://purl.uniprot.org/core/name | "J Cell Physiol"xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://purl.uniprot.org/core/pages | "1980-1995"xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://purl.uniprot.org/core/title | "Reversion-inducing cysteine-rich protein with Kazal motifs and MT1-MMP promote the formation of robust fibrillin fibers."xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://purl.uniprot.org/core/volume | "236"xsd:string |
| http://purl.uniprot.org/citations/32730638 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32730638 |
| http://purl.uniprot.org/citations/32730638 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32730638 |
| http://purl.uniprot.org/uniprot/#_A0A6M3WJI3-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_A0A1B1PFX5-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_A0A384MDM4-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_A2RSP9-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_B2RCE6-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_B4E3I6-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_A8K9D8-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_P53690-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_L8E775-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_L8E6V0-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |
| http://purl.uniprot.org/uniprot/#_Q75N88-mappedCitation-32730638 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32730638 |