http://purl.uniprot.org/citations/32735900 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/32735900 | http://www.w3.org/2000/01/rdf-schema#comment | "Based on genome-scale loss-of-function screens we discovered that Topoisomerase III-β (TOP3B), a human topoisomerase that acts on DNA and RNA, is required for yellow fever virus and dengue virus-2 replication. Remarkably, we found that TOP3B is required for efficient replication of all positive-sense-single stranded RNA viruses tested, including SARS-CoV-2. While there are no drugs that specifically inhibit this topoisomerase, we posit that TOP3B is an attractive anti-viral target."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.antiviral.2020.104874"xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Bedford M.T."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Xie X."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Hirano M."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Bukreyev A."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Rajsbaum R."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Bradrick S.S."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Garcia-Blanco M.A."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Shi P.Y."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Shan C."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Hage A."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Fagg W.S."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Prasanth K.R."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "McAnarney E.T."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Menachery V."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/author | "Pietzsch C.A."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/name | "Antiviral Res"xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/pages | "104874"xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/title | "Topoisomerase III-beta is required for efficient replication of positive-sense RNA viruses."xsd:string |
http://purl.uniprot.org/citations/32735900 | http://purl.uniprot.org/core/volume | "182"xsd:string |
http://purl.uniprot.org/citations/32735900 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32735900 |
http://purl.uniprot.org/citations/32735900 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32735900 |