| http://purl.uniprot.org/citations/32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/32737121 | http://www.w3.org/2000/01/rdf-schema#comment | "Transcriptomes may evolve by multiple mechanisms, including the evolution of novel genes, the evolution of transcript abundance, and the evolution of cell, tissue, or organ expression patterns. Here, we focus on the last of these mechanisms in an investigation of tissue and organ shifts in gene expression in Drosophila melanogaster. In contrast to most investigations of expression evolution, we seek to provide a framework for understanding the mechanisms of novel expression patterns on a short population genetic timescale. To do so, we generated population samples of D. melanogaster transcriptomes from five tissues: accessory gland, testis, larval salivary gland, female head, and first-instar larva. We combined these data with comparable data from two outgroups to characterize gains and losses of expression, both polymorphic and fixed, in D. melanogaster We observed a large number of gain- or loss-of-expression phenotypes, most of which were polymorphic within D. melanogaster Several polymorphic, novel expression phenotypes were strongly influenced by segregating cis-acting variants. In support of previous literature on the evolution of novelties functioning in male reproduction, we observed many more novel expression phenotypes in the testis and accessory gland than in other tissues. Additionally, genes showing novel expression phenotypes tend to exhibit greater tissue-specific expression. Finally, in addition to qualitatively novel expression phenotypes, we identified genes exhibiting major quantitative expression divergence in the D. melanogaster lineage."xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://purl.org/dc/terms/identifier | "doi:10.1534/genetics.120.303515"xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://purl.uniprot.org/core/author | "Begun D.J."xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://purl.uniprot.org/core/author | "Cridland J.M."xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://purl.uniprot.org/core/author | "Majane A.C."xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://purl.uniprot.org/core/author | "Sheehy H.K."xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/32737121 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://purl.uniprot.org/core/pages | "79-93"xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://purl.uniprot.org/core/title | "Polymorphism and Divergence of Novel Gene Expression Patterns in Drosophila melanogaster."xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://purl.uniprot.org/core/volume | "216"xsd:string |
| http://purl.uniprot.org/citations/32737121 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32737121 |
| http://purl.uniprot.org/citations/32737121 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32737121 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFU4-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KF05-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFD0-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |
| http://purl.uniprot.org/uniprot/#_A0A0S0WNT6-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K7X4-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LHI0-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K684-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K7M8-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |
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| http://purl.uniprot.org/uniprot/#_B7Z110-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |
| http://purl.uniprot.org/uniprot/#_A1A6Q4-mappedCitation-32737121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32737121 |