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http://purl.uniprot.org/citations/32784485http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/32784485http://www.w3.org/2000/01/rdf-schema#comment"The Wnt/CTNNB1 pathway is often deregulated in epithelial tumors. The ZFP36 gene, encoding the mRNA binding protein Tristetraprolin (TTP), is downregulated in several cancers, where it has been described to behave as a tumor suppressor. By this report, we show that Wnt/CTNNB1 pathway is constitutively activated, and ZFP36 expression is downregulated in Squamous Cell Carcinoma (SCC) cell lines compared to normal keratinocytes. Moreover, we suggest that the decrease of ZFP36 expression might depend on the activity of transcriptional repressors SNAI1, SLUG and TWIST, whose expression is induced by Wnt/CTNNB1, highlighting a potential regulatory mechanism underlying ZFP36 downregulation in epithelial cancers."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.org/dc/terms/identifier"doi:10.3390/ijms21165692"xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/author"Marconi A."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/author"Grande A."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/author"Zanocco-Marani T."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/author"Bertesi M."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/author"Manfredini R."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/author"Lotti R."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/author"Pincelli C."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/author"Fantini S."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/author"Zanfi E.D."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/date"2020"xsd:gYear
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/name"Int J Mol Sci"xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/pages"E5692"xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/title"Wnt/CTNNB1 Signal Transduction Pathway Inhibits the Expression of ZFP36 in Squamous Cell Carcinoma, by Inducing Transcriptional Repressors SNAI1, SLUG and TWIST."xsd:string
http://purl.uniprot.org/citations/32784485http://purl.uniprot.org/core/volume"21"xsd:string
http://purl.uniprot.org/citations/32784485http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/32784485
http://purl.uniprot.org/citations/32784485http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/32784485
http://purl.uniprot.org/uniprot/#_Q15672-mappedCitation-32784485http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32784485
http://purl.uniprot.org/uniprot/#_M0QY76-mappedCitation-32784485http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32784485
http://purl.uniprot.org/uniprot/#_O95863-mappedCitation-32784485http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32784485
http://purl.uniprot.org/uniprot/#_P26651-mappedCitation-32784485http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/32784485
http://purl.uniprot.org/uniprot/O95863http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/32784485
http://purl.uniprot.org/uniprot/Q15672http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/32784485