| http://purl.uniprot.org/citations/32814254 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/32814254 | http://www.w3.org/2000/01/rdf-schema#comment | "Peptide presentation on MHC class I molecules (MHC-I) is central to mounting effective antiviral and antitumoral immune responses. The tapasin-related protein TAPBPR is an MHC-I peptide editor which shapes the final peptide repertoire displayed on the cell surface. Here, we review recent findings which further elucidate the mechanisms by which TAPBPR performs peptide editing on a molecular level, and how glycosylation on MHC-I influences the interaction with TAPBPR and the peptide loading complex. We also explore how the function of TAPBPR can be utilized to promote exogenous peptide loading directly onto plasma-membrane expressed MHC-I. This has led to the development of new assays to investigate TAPBPR-mediated peptide editing and uncovered translational opportunities of utilizing TAPBPR to treat human disease."xsd:string |
| http://purl.uniprot.org/citations/32814254 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.coi.2020.06.004"xsd:string |
| http://purl.uniprot.org/citations/32814254 | http://purl.uniprot.org/core/author | "Boyle L.H."xsd:string |
| http://purl.uniprot.org/citations/32814254 | http://purl.uniprot.org/core/author | "Ilca T."xsd:string |
| http://purl.uniprot.org/citations/32814254 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/32814254 | http://purl.uniprot.org/core/name | "Curr Opin Immunol"xsd:string |
| http://purl.uniprot.org/citations/32814254 | http://purl.uniprot.org/core/pages | "146-151"xsd:string |
| http://purl.uniprot.org/citations/32814254 | http://purl.uniprot.org/core/title | "The Ins and Outs of TAPBPR."xsd:string |
| http://purl.uniprot.org/citations/32814254 | http://purl.uniprot.org/core/volume | "64"xsd:string |
| http://purl.uniprot.org/citations/32814254 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32814254 |
| http://purl.uniprot.org/citations/32814254 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32814254 |
| http://purl.uniprot.org/uniprot/#_G3V1T3-mappedCitation-32814254 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32814254 |
| http://purl.uniprot.org/uniprot/#_Q53GH5-mappedCitation-32814254 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32814254 |
| http://purl.uniprot.org/uniprot/#_Q53FW8-mappedCitation-32814254 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32814254 |
| http://purl.uniprot.org/uniprot/#_Q9BX59-mappedCitation-32814254 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32814254 |
| http://purl.uniprot.org/uniprot/Q53GH5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32814254 |
| http://purl.uniprot.org/uniprot/G3V1T3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32814254 |
| http://purl.uniprot.org/uniprot/Q53FW8 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32814254 |
| http://purl.uniprot.org/uniprot/Q9BX59 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/32814254 |