| http://purl.uniprot.org/citations/32841718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/32841718 | http://www.w3.org/2000/01/rdf-schema#comment | "C-type lectins (CTLs) recognize various glycoconjugates through carbohydrate recognition domains (CRDs) and they play important roles in immune responses. In this study, comparative genomic analysis of CTLs were performed in 7 holometabolous species. CTL-S1 to S8 and CTL-X1 to X4 orthologous groups existed in the 7 species, while CTL-X5 group with dual-CRD, CTL-S11 group with triple-CRD, CTL-S9 group with a long C-terminus and Lepidopteran specific CTL-S10 group were not conserved. SliCTL-S12 to S14 cluster was only present in Spodoptera litura, and CTL-S genes were expanded on chromosomes 2 L and 2 R in Drosophila melanogaster. Most IMLs were clustered into three groups and the numbers of IMLs vary among species due to gene duplications. D. melanogaster specific CTLs and Lepidopteran IMLs within each of the three groups evolved more rapidly with higher dN/dS ratios. Two CRDs in IMLs clustered into two clades, with conserved Cys4-Cys5 and Cys1-Cys2 bonds in the first and second CRDs, respectively. The CTL-S and CTL-X family members in S. litura were mainly expressed in the fat body of 5th but not 6th instar larvae, and responded differently to S. litura nucleopolyhedrovirus (SpltNPV) and Nomuraea rileyi infection. The transcription levels of SliCTLs that expressed in fat body but not highly expressed in hemocytes were decreased at the middle and late stages of SpltNPV infection, and the mRNA levels of SliCTLs highly or specifically expressed in hemocytes were mainly decreased by SpltlNPV, N. rileyi and Bacillus thuringiensis infection. These results provide valuable information for further exploration of CTL functions in host-pathogen interaction."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ibmb.2020.103451"xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/author | "Hu Q."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/author | "Lu Y."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/author | "Li Q."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/author | "Zhang R."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/author | "Zhu K."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/author | "Zhu M."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/author | "Su F."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/author | "Yu X.Q."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/name | "Insect Biochem Mol Biol"xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/pages | "103451"xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/title | "Comparative genomic analysis of C-type lectin-domain genes in seven holometabolous insect species."xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://purl.uniprot.org/core/volume | "126"xsd:string |
| http://purl.uniprot.org/citations/32841718 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32841718 |
| http://purl.uniprot.org/citations/32841718 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/32841718 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KEZ3-mappedCitation-32841718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32841718 |
| http://purl.uniprot.org/uniprot/#_E1JHA6-mappedCitation-32841718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32841718 |
| http://purl.uniprot.org/uniprot/#_A0A0B4JCT4-mappedCitation-32841718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32841718 |
| http://purl.uniprot.org/uniprot/#_A1Z7Z6-mappedCitation-32841718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32841718 |
| http://purl.uniprot.org/uniprot/#_A1Z8L7-mappedCitation-32841718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32841718 |
| http://purl.uniprot.org/uniprot/#_B4ZJ93-mappedCitation-32841718 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/32841718 |