| http://purl.uniprot.org/citations/3284177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3284177 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3284177 | http://www.w3.org/2000/01/rdf-schema#comment | "We have mapped the vaccinia virus (VV) gene encoding the large subunit of ribonucleotide reductase (VV M1) within the HindIII I restriction fragment by using an oligonucleotide probe. Nucleotide sequencing revealed a 2340-bp open reading frame (orf), 1-3, whose amino acid sequence is highly homologous to the mouse M1 protein. The 1-3 gene was expressed as an immediate-early gene product, being transcribed in a leftward direction into a 2.7-kb polyadenylated transcript. Hybrid-selected translation of cycloheximide-amplified immediate-early viral RNA demonstrated that this mRNA encoded an 86-kd protein, which agrees with the expected size of the reductase large subunit. The 5'- and 3'-boundaries of the 1-3 transcriptional unit were determined by primer extension and S1-nuclease analysis, respectively, and shown to contain sequence elements typical of other VV early genes. Surprisingly, the predicted amino acid sequence of the VV enzyme subunit shares 72.5% homology with the mouse large subunit, M1."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.org/dc/terms/identifier | "doi:10.1016/0042-6822(88)90627-7"xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.org/dc/terms/identifier | "doi:10.1016/0042-6822(88)90627-7"xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/author | "Hruby D.E."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/author | "Hruby D.E."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/author | "Slabaugh M.B."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/author | "Slabaugh M.B."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/author | "Bibler J.K."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/author | "Bibler J.K."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/author | "Tengelsen L.A."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/author | "Tengelsen L.A."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/pages | "121-131"xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/pages | "121-131"xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/title | "Nucleotide sequence and molecular genetic analysis of the large subunit of ribonucleotide reductase encoded by vaccinia virus."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/title | "Nucleotide sequence and molecular genetic analysis of the large subunit of ribonucleotide reductase encoded by vaccinia virus."xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/volume | "164"xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://purl.uniprot.org/core/volume | "164"xsd:string |
| http://purl.uniprot.org/citations/3284177 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3284177 |
| http://purl.uniprot.org/citations/3284177 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/3284177 |