http://purl.uniprot.org/citations/32855967 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/32855967 | http://www.w3.org/2000/01/rdf-schema#comment | "Human gastric cancer is one of the most common malignant tumors with a poor prognosis. Cisplatin (CDDP) is a well-known first-line chemotherapeutic drug. Acquired resistance retards the clinical application of CDDP in gastric cancer. In this study, circular RNA circ_0026359 was demonstrated to be overexpressed in gastric cancer tissues/cells compared with normal gastric tissues/cells and was overexpressed in CDDP-resistant gastric cancer tissues/cells compared with CDDP-sensitive gastric cancer tissues/cells. High levels of circ_0026359 were associated with low overall survival (OS) and relapse-free survival (RFS) rates in gastric cancer patients. circ_0026359 was examined to promote CDDP resistance in gastric cancer cells. circ_0026359 directly interacted and negatively regulated miR-1200. POLD4 was a direct target of miR-1200. miR-1200/POLD4 pathway mediated the promoting role of circ_0026359 in CDDP resistance of gastric cancer. circ_0026359 could be used as a potential target for CDDP-resistant gastric cancer therapy."xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.org/dc/terms/identifier | "doi:10.1155/2020/5103272"xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/author | "Chang J."xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/author | "Zhang Z."xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/author | "Yu X."xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/author | "Zhou B."xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/name | "Biomed Res Int"xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/pages | "5103272"xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/title | "Circular RNA circ_0026359 Enhances Cisplatin Resistance in Gastric Cancer via Targeting miR-1200/POLD4 Pathway."xsd:string |
http://purl.uniprot.org/citations/32855967 | http://purl.uniprot.org/core/volume | "2020"xsd:string |
http://purl.uniprot.org/citations/32855967 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/32855967 |
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