http://purl.uniprot.org/citations/3290053 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3290053 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/3290053 | http://www.w3.org/2000/01/rdf-schema#comment | "We report the isolation and nucleotide sequence determination of a beta-tubulin gene (TUB2) from the pathogenic dimorphic fungus Candida albicans. Nucleotide sequence analysis revealed that TUB2 encodes a protein of 449 amino acids (aa) with considerable sequence homology to beta-tubulins isolated from other fungal species. The nucleotide sequence of the C. albicans gene is 70% homologous to that of the Saccharomyces cerevisiae gene. The coding region for the C. albicans beta-tubulin gene is interrupted by two introns. The first intron occurs after the 4th aa and the second intron occurs after the 13th aa. A comparison with other fungal beta-tubulin genes indicates that the intron locations are highly conserved. Codon usage in the C. albicans TUB2 gene is nonrandom, as has been observed for other fungal beta-tubulin genes. The C. albicans TUB2 gene is transcribed to yield a 1.8-kb mRNA species. On the basis of genomic Southern-blot analysis, we conclude that C. albicans most likely possesses a single beta-tubulin gene."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.org/dc/terms/identifier | "doi:10.1016/0378-1119(88)90545-8"xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.org/dc/terms/identifier | "doi:10.1016/0378-1119(88)90545-8"xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Koltin Y."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Koltin Y."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Smith R.A."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Smith R.A."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Gorman J.A."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Gorman J.A."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Allaudeen H.S."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Allaudeen H.S."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Whitman M.H."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/author | "Whitman M.H."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/pages | "53-63"xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/pages | "53-63"xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/title | "Isolation and characterization of a beta-tubulin gene from Candida albicans."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/title | "Isolation and characterization of a beta-tubulin gene from Candida albicans."xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/volume | "63"xsd:string |
http://purl.uniprot.org/citations/3290053 | http://purl.uniprot.org/core/volume | "63"xsd:string |