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| http://purl.uniprot.org/citations/32936932 | http://www.w3.org/2000/01/rdf-schema#comment | "The Saccharomyces cerevisiae Mus81-Mms4 complex is a highly conserved DNA structure-specific endonuclease that plays essential roles in the processing of recombination intermediates that arise during the repair of stalled replication forks and double-stranded breaks. To identify novel factors functioning conjointly with Mus81-Mms4, we performed a biochemical screen and found that Crp1, a cruciform DNA-recognizing protein that specifically binds to DNA four-way junction structures, could stimulate the Mus81-Mms4 endonuclease. The specific protein interaction between Mus81-Mms4 and Crp1 was responsible for the stimulation observed. Multicopy expression of Crp1 could partially rescue the sensitivity to DNA-damaging agents of the sgs1∆mus81∆21-24N mutant. Our results provide insight into the functional role and interaction of Crp1 with other proteins involved in DNA repair."xsd:string |
| http://purl.uniprot.org/citations/32936932 | http://purl.org/dc/terms/identifier | "doi:10.1002/1873-3468.13931"xsd:string |
| http://purl.uniprot.org/citations/32936932 | http://purl.uniprot.org/core/author | "Tran D.H."xsd:string |
| http://purl.uniprot.org/citations/32936932 | http://purl.uniprot.org/core/author | "Nguyen T.X."xsd:string |
| http://purl.uniprot.org/citations/32936932 | http://purl.uniprot.org/core/author | "Phung H.T.T."xsd:string |
| http://purl.uniprot.org/citations/32936932 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/32936932 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/32936932 | http://purl.uniprot.org/core/pages | "4320-4337"xsd:string |
| http://purl.uniprot.org/citations/32936932 | http://purl.uniprot.org/core/title | "The cruciform DNA-binding protein Crp1 stimulates the endonuclease activity of Mus81-Mms4 in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/32936932 | http://purl.uniprot.org/core/volume | "594"xsd:string |
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