| http://purl.uniprot.org/citations/33004803 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33004803 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33004803 | http://www.w3.org/2000/01/rdf-schema#comment | "Self-incompatibility (SI) is a breeding system that promotes cross-fertilization. In Brassica, pollen rejection is induced by a haplotype-specific interaction between pistil determinant SRK (S receptor kinase) and pollen determinant SP11 (S-locus Protein 11, also named SCR) from the S-locus. Although the structure of the B. rapa S9-SRK ectodomain (eSRK) and S9-SP11 complex has been determined, it remains unclear how SRK discriminates self- and nonself-SP11. Here, we uncover the detailed mechanism of self/nonself-discrimination in Brassica SI by determining the S8-eSRK-S8-SP11 crystal structure and performing molecular dynamics (MD) simulations. Comprehensive binding analysis of eSRK and SP11 structures reveals that the binding free energies are most stable for cognate eSRK-SP11 combinations. Residue-based contribution analysis suggests that the modes of eSRK-SP11 interactions differ between intra- and inter-subgroup (a group of phylogenetically neighboring haplotypes) combinations. Our data establish a model of self/nonself-discrimination in Brassica SI."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-020-18698-w"xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41467-020-18698-w"xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Fujii S."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Fujii S."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Liu X."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Liu X."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Mori T."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Mori T."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Shimizu K."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Shimizu K."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Terada T."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Terada T."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Watanabe M."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Watanabe M."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Takada Y."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Takada Y."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Nagata K."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Nagata K."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Mishima M."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Mishima M."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Hirano Y."xsd:string |
| http://purl.uniprot.org/citations/33004803 | http://purl.uniprot.org/core/author | "Hirano Y."xsd:string |