| http://purl.uniprot.org/citations/33025841 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33025841 | http://www.w3.org/2000/01/rdf-schema#comment | "The objective of this meta-analysis was to estimate the association of ACE I/D, -240 A > T and AT1R 1166 A > C polymorphisms with breast cancer (BC) risk. A comprehensive search on databases was conducted to identify all eligible case-control studies. Finally, 35 case-control studies, including 20 studies for ACE I/D, seven studies for ACE 240 A > T, and eight studies for AT1R 1166 A > C were included. The pooled analysis showed a significant association between ACE I/D polymorphism and BC risk under three genetic models, i.e., heterozygote (ID vs. DD: OR = 0.707, 95% CI 0.528-0.946, p = 0.020), homozygote (II vs. DD: OR = 0.662, 95% CI 0.462-0.947, p = 0.024), and dominant (II + ID vs. DD: OR = 0.691, 95% CI 0.507-0.941, p = 0.019). A significant association was also observed in ACE I/D polymorphism with BC risk among Asians and Caucasians. However, ACE -240 A > T and AT1R 1166 A > C polymorphisms were not associated with BC. Stratified analyses by ethnicity showed a significant association of ACE -240 A > T and AT1R 1166 A > C polymorphisms with BC risk in Latinos populations, but not in Asians. This meta-analysis inconsistence with all previous meta-analyses suggests that the ACE I/D might be associated with BC in overall and by ethnicity. However, the ACE -240 A > T and AT1R 1166 A > C were associated with BC risk only among Latinos populations."xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.org/dc/terms/identifier | "doi:10.1080/15257770.2020.1826515"xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/author | "Karimi-Zarchi M."xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/author | "Akbarian E."xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/author | "Neamatzadeh H."xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/author | "Dastgheib S.A."xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/author | "Farbod M."xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/author | "Meibodi B."xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/author | "Asadian F."xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/name | "Nucleosides Nucleotides Nucleic Acids"xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/pages | "117-135"xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/title | "Association of ACE I/D, -240A > T and AT1R A1166C polymorphisms with susceptibility to breast cancer: a systematic review and meta-analysis based on 35 case-control studies."xsd:string |
| http://purl.uniprot.org/citations/33025841 | http://purl.uniprot.org/core/volume | "40"xsd:string |
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