| http://purl.uniprot.org/citations/33033119 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33033119 | http://www.w3.org/2000/01/rdf-schema#comment | "Animal germ cells communicate directly with each other during gametogenesis through intercellular bridges, often called ring canals (RCs), that form as a consequence of incomplete cytokinesis during cell division. Developing germ cells in Drosophila have an additional specialized organelle connecting the cells called the fusome. Ring canals and the fusome are required for fertility in Drosophila females, but little is known about their roles during spermatogenesis. With live imaging, we directly observe the intercellular movement of GFP and a subset of endogenous proteins through RCs during spermatogenesis, from two-cell diploid spermatogonia to clusters of 64 post-meiotic haploid spermatids, demonstrating that RCs are stable and open to intercellular traffic throughout spermatogenesis. Disruption of the fusome, a large cytoplasmic structure that extends through RCs and is important during oogenesis, had no effect on spermatogenesis or male fertility under normal conditions. Our results reveal that male germline RCs allow the sharing of cytoplasmic information that might play a role in quality control surveillance during sperm development."xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.190140"xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/author | "Cooley L."xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/author | "Kaufman R.S."xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/author | "Price K.L."xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/author | "Hudson A.M."xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/author | "Mannix K.M."xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/author | "Ayers K.M."xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/pages | "dev190140"xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/title | "Drosophila sperm development and intercellular cytoplasm sharing through ring canals do not require an intact fusome."xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://purl.uniprot.org/core/volume | "147"xsd:string |
| http://purl.uniprot.org/citations/33033119 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33033119 |
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