DESCRIBE <http://purl.uniprot.org/citations/33109565>

Subject	Predicate	Object
http://purl.uniprot.org/citations/33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/33109565	http://www.w3.org/2000/01/rdf-schema#comment	" Background/aim To determine the differential protein profiles of cervical cancer cell lines in order to find potential targets that can be used as biomarkers in low-grade squamous intraepithelial lesions (LSIL) diagnosis. Materials and methods Proteomic analysis was performed on cervical cancer cell lines by 2D electrophoresis and liquid chromatography-mass spectrometry. Biomarker validation was performed in histological samples by immunofluorescence. Results Aldo-keto reductase C1 (AKR1C1) and transketolase-like 1 (TKTL1) proteins were selected as biomarkers and their expression was increased in samples with LSIL diagnosis. TKTL1 in combination with AKR1C1 increased sensitivity and specificity to 75% and 66%, respectively, with an area under curve of 0.76 in receiver operating characteristics curve analysis. Conclusion AKR1C1 and TKTL1 showed potential as biomarkers for diagnosis of LSIL in Mexican women, with similar sensitivity and specificity to the biomarkers used in clinical trials for diagnosis of LSIL."xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.org/dc/terms/identifier	"doi:10.21873/anticanres.14648"xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/author	"Del Carmen Cardenas-Aguayo M."xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/author	"Espinosa-Montesinos A."xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/author	"JimEnez A."xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/author	"RamOn-Gallegos E."xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/author	"Sequeda-JuArez A."xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/date	"2020"xsd:gYear
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/name	"Anticancer Res"xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/pages	"6273-6284"xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/title	"Use of AKR1C1 and TKTL1 in the Diagnosis of Low-grade Squamous Intraepithelial Lesions from Mexican Women."xsd:string
http://purl.uniprot.org/citations/33109565	http://purl.uniprot.org/core/volume	"40"xsd:string
http://purl.uniprot.org/citations/33109565	http://www.w3.org/2004/02/skos/core#exactMatch	http://purl.uniprot.org/pubmed/33109565
http://purl.uniprot.org/citations/33109565	http://xmlns.com/foaf/0.1/primaryTopicOf	https://pubmed.ncbi.nlm.nih.gov/33109565
http://purl.uniprot.org/uniprot/#_A2ID95-mappedCitation-33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/33109565
http://purl.uniprot.org/uniprot/#_A2ID96-mappedCitation-33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/33109565
http://purl.uniprot.org/uniprot/#_B7Z7A6-mappedCitation-33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/33109565
http://purl.uniprot.org/uniprot/#_B7Z7I0-mappedCitation-33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/33109565
http://purl.uniprot.org/uniprot/#_B7Z7M4-mappedCitation-33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/33109565
http://purl.uniprot.org/uniprot/#_A8K859-mappedCitation-33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/33109565
http://purl.uniprot.org/uniprot/#_B4E0M1-mappedCitation-33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/33109565
http://purl.uniprot.org/uniprot/#_P51854-mappedCitation-33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/33109565
http://purl.uniprot.org/uniprot/#_Q04828-mappedCitation-33109565	http://www.w3.org/1999/02/22-rdf-syntax-ns#object	http://purl.uniprot.org/citations/33109565
http://purl.uniprot.org/uniprot/B7Z7A6	http://purl.uniprot.org/core/mappedCitation	http://purl.uniprot.org/citations/33109565