| http://purl.uniprot.org/citations/33177158 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33177158 | http://www.w3.org/2000/01/rdf-schema#comment | "The RIG-I receptor induces the innate antiviral responses upon sensing RNA viruses. The mechanisms through which RIG-I optimizes the strength of the downstream signaling remain incompletely understood. In this study, we identified that NSUN5 could potentiate the RIG-I innate signaling pathway. Deficiency of NSUN5 enhanced RNA virus proliferation and inhibited the induction of the downstream antiviral genes. Consistently, NSUN5-deficient mice were more susceptible to RNA virus infection than their wild-type littermates. Mechanistically, NSUN5 bound directly to both viral RNA and RIG-I, synergizing the recognition of dsRNA by RIG-I. Collectively, to our knowledge, this study characterized NSUN5 as a novel RIG-I coreceptor, playing a vital role in restricting RNA virus infection."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.1901455"xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Hu H."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Li C."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Sun B."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Wang C."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Wang Q."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Zhang L."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Zhu J."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Zeng H."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Meng W."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Liang J."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/author | "Ye F."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/pages | "3408-3418"xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/title | "NSUN5 Facilitates Viral RNA Recognition by RIG-I Receptor."xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://purl.uniprot.org/core/volume | "205"xsd:string |
| http://purl.uniprot.org/citations/33177158 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33177158 |
| http://purl.uniprot.org/citations/33177158 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/33177158 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YTU6-mappedCitation-33177158 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33177158 |
| http://purl.uniprot.org/uniprot/#_A1L0V6-mappedCitation-33177158 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33177158 |
| http://purl.uniprot.org/uniprot/#_A7YY79-mappedCitation-33177158 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33177158 |
| http://purl.uniprot.org/uniprot/#_A2AP29-mappedCitation-33177158 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33177158 |