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http://purl.uniprot.org/citations/33179626 | http://www.w3.org/2000/01/rdf-schema#comment | "Acid sphingomyelinase (ASM) is a potential drug target and involved in rapid lipid signalling events. However, there are no tools available to adequately study such processes. Based on a non cell-permeable PtdIns(3,5)P2 inhibitor of ASM, we developed a compound with o-nitrobenzyl photocages and butyryl esters to transiently mask hydroxyl groups. This resulted in a potent light-inducible photocaged ASM inhibitor (PCAI). The first example of a time-resolved inhibition of ASM was shown in intact living cells."xsd:string |
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http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/author | "Arenz C."xsd:string |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/author | "Kleuser B."xsd:string |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/author | "Schumacher F."xsd:string |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/author | "Kappe C."xsd:string |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/author | "Naseri G."xsd:string |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/author | "Prause K."xsd:string |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/name | "Chem Commun (Camb)"xsd:string |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/pages | "14885-14888"xsd:string |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/title | "A photocaged inhibitor of acid sphingomyelinase."xsd:string |
http://purl.uniprot.org/citations/33179626 | http://purl.uniprot.org/core/volume | "56"xsd:string |
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