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http://purl.uniprot.org/citations/33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/33179626http://www.w3.org/2000/01/rdf-schema#comment"Acid sphingomyelinase (ASM) is a potential drug target and involved in rapid lipid signalling events. However, there are no tools available to adequately study such processes. Based on a non cell-permeable PtdIns(3,5)P2 inhibitor of ASM, we developed a compound with o-nitrobenzyl photocages and butyryl esters to transiently mask hydroxyl groups. This resulted in a potent light-inducible photocaged ASM inhibitor (PCAI). The first example of a time-resolved inhibition of ASM was shown in intact living cells."xsd:string
http://purl.uniprot.org/citations/33179626http://purl.org/dc/terms/identifier"doi:10.1039/d0cc06661c"xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/author"Arenz C."xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/author"Kleuser B."xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/author"Schumacher F."xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/author"Kappe C."xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/author"Naseri G."xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/author"Prause K."xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/date"2020"xsd:gYear
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/name"Chem Commun (Camb)"xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/pages"14885-14888"xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/title"A photocaged inhibitor of acid sphingomyelinase."xsd:string
http://purl.uniprot.org/citations/33179626http://purl.uniprot.org/core/volume"56"xsd:string
http://purl.uniprot.org/citations/33179626http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/33179626
http://purl.uniprot.org/citations/33179626http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/33179626
http://purl.uniprot.org/uniprot/#_Q15496-mappedCitation-33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33179626
http://purl.uniprot.org/uniprot/#_E9LUE6-mappedCitation-33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33179626
http://purl.uniprot.org/uniprot/#_E9LUE7-mappedCitation-33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33179626
http://purl.uniprot.org/uniprot/#_E9LUE8-mappedCitation-33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33179626
http://purl.uniprot.org/uniprot/#_E9LUE9-mappedCitation-33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33179626
http://purl.uniprot.org/uniprot/#_G3V1E1-mappedCitation-33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33179626
http://purl.uniprot.org/uniprot/#_P17405-mappedCitation-33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33179626
http://purl.uniprot.org/uniprot/#_Q59EN6-mappedCitation-33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33179626
http://purl.uniprot.org/uniprot/#_Q13810-mappedCitation-33179626http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/33179626