| http://purl.uniprot.org/citations/3325742 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/3325742 | http://www.w3.org/2000/01/rdf-schema#comment | "The induction of the cytoplasmic 'petite' mutation (or rho-) after photoaddition of either 8-methoxypsoralen (8-MOP) or 3-carbethoxypsoralen (3-CPs), after 254 nm u.v. and after 6-N-hydroxyaminopurine treatment was examined in three pso mutants in comparison to wild-type Saccharomyces cerevisiae. In three pso mutants which are defective in the induction of nuclear reverse and forward mutations, the photoaddition of 8-MOP enhanced the induction of rho-. This was true for cells in both exponential and stationary phases of growth. After photoaddition of 3-CPs in both growth phases the frequency of rho-was enhanced in pso3-1 whereas pso1-1 showed the same response as the wild-type. In pso2-1 the frequency of rho-was reduced. After treatment with 254 nm u.v. in the stationary phase of growth, rho-induction was increased in pso1-1 and pso3-1 cells as compared to wild-type cells. However, when treated in the exponential phase of growth all three pso mutants showed reduced rho-frequency. The data indicate that the defect in the repair of furocoumarins plus light-induced lesions controlled by nuclear genes (pso) interferes to various extents with the fate of mitochondrial lesions. The frequency of rho-mutants induced in the pso mutants by an analogue of adenine, 6-N-hydroxyaminopurine, was similar to that observed in the wild-type strain, suggesting that this drug may also act at the mitochondrial level as a direct mutagen in yeast."xsd:string |
| http://purl.uniprot.org/citations/3325742 | http://purl.org/dc/terms/identifier | "doi:10.1093/mutage/2.3.187"xsd:string |
| http://purl.uniprot.org/citations/3325742 | http://purl.uniprot.org/core/author | "Henriques J.A."xsd:string |
| http://purl.uniprot.org/citations/3325742 | http://purl.uniprot.org/core/author | "Da Silva K.V."xsd:string |
| http://purl.uniprot.org/citations/3325742 | http://purl.uniprot.org/core/date | "1987"xsd:gYear |
| http://purl.uniprot.org/citations/3325742 | http://purl.uniprot.org/core/name | "Mutagenesis"xsd:string |
| http://purl.uniprot.org/citations/3325742 | http://purl.uniprot.org/core/pages | "187-197"xsd:string |
| http://purl.uniprot.org/citations/3325742 | http://purl.uniprot.org/core/title | "Induction of the cytoplasmic 'petite' mutation in pso mutants of Saccharomyces cerevisiae by photoaddition of furocoumarins or by ultraviolet radiation."xsd:string |
| http://purl.uniprot.org/citations/3325742 | http://purl.uniprot.org/core/volume | "2"xsd:string |
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