| http://purl.uniprot.org/citations/33287942 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/33287942 | http://www.w3.org/2000/01/rdf-schema#comment | "Ovarian cancer is a leading cause of gynecological cancer-related mortality. It has been reported that miR-409-3p is involved in the proliferation and migration of cancer cells. However, the role of miR-409-3p in ovarian cancer has not been well studied. The present study aimed to investigate the functional role of miR-409-3p in the pathogenesis of ovarian cancer, and its potential mechanism. It was found that the expression levels of miR-409-3p in 6 ovarian cancer tissues were upregulated. Through proliferation, migration and colony formation assays, it was revealed that overexpression of miR-409-3p inhibited the proliferation and migration of ovarian cancer cells. It was predicted from bioinformatics assays that the complementary binding sites were within miR-409-3p and Rab10. It was also demonstrated that the downregulation of the expression of Rab10 reversed the miR-409-3p downregulation-induced abnormal proliferation of ovarian cancer cells. These results suggest that miR-409-3p expression can be used as a predictive marker for the prognosis of ovarian cancer. Thus, the miR-409-3p/Rab10 axis may be a novel therapeutic target for ovarian cancer."xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/author | "Chen L."xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/author | "Hu H."xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/author | "Zhang B."xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/author | "Ohno Y."xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/date | "2020"xsd:gYear |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/name | "Cell Mol Biol (Noisy-le-grand)"xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/pages | "197-201"xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/title | "miR-409-3p inhibits the proliferation and migration of human ovarian cancer cells by targeting Rab10."xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://purl.uniprot.org/core/volume | "66"xsd:string |
| http://purl.uniprot.org/citations/33287942 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33287942 |
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