http://purl.uniprot.org/citations/33471580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/33471580 | http://www.w3.org/2000/01/rdf-schema#comment | "Aim: This study aims to examine the DNA methylation (DNAm) and expression patterns of genes associated with placental angiogenesis in preeclampsia. Materials & methods: DNAm and expression were examined in normotensive (n = 100) and preeclampsia (n = 100) women using pyrosequencing and quantitative real-time PCR respectively. Results: Hypomethylation at several CpGs was observed in PlGF and FLT-1 in women with preeclampsia compared to normotensive controls. PlGF expression was lower in women with preeclampsia while FLT-1 expression was comparable. DNAm at various CpGs was negatively correlated with expression in both the genes and were associated with maternal blood pressure and birth outcomes. Conclusion: DNAm and expression of angiogenic factors in placentae are differentially regulated in preeclampsia and influence birth outcomes."xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.org/dc/terms/identifier | "doi:10.2217/epi-2020-0318"xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/author | "Chandak G.R."xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/author | "Joshi S.R."xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/author | "Kaur L."xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/author | "Mehendale S.S."xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/author | "Sundrani D.P."xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/author | "M Dave K."xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/author | "Randhir K.N."xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/date | "2021"xsd:gYear |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/name | "Epigenomics"xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/pages | "257-269"xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/title | "Placental growth factor and Fms related tyrosine kinase-1 are hypomethylated in preeclampsia placentae."xsd:string |
http://purl.uniprot.org/citations/33471580 | http://purl.uniprot.org/core/volume | "13"xsd:string |
http://purl.uniprot.org/citations/33471580 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/33471580 |
http://purl.uniprot.org/citations/33471580 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/33471580 |
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http://purl.uniprot.org/uniprot/#_H9N1E8-mappedCitation-33471580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33471580 |
http://purl.uniprot.org/uniprot/#_B5A924-mappedCitation-33471580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33471580 |
http://purl.uniprot.org/uniprot/#_B1AC84-mappedCitation-33471580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33471580 |
http://purl.uniprot.org/uniprot/#_P17948-mappedCitation-33471580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33471580 |
http://purl.uniprot.org/uniprot/#_L7RSL3-mappedCitation-33471580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33471580 |
http://purl.uniprot.org/uniprot/#_Q16332-mappedCitation-33471580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33471580 |
http://purl.uniprot.org/uniprot/#_Q16333-mappedCitation-33471580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/33471580 |